Hydrocortisone
- Generic Name
- Hydrocortisone
- Brand Names
- Ala-cort, Ala-scalp, Alcortin, Alkindi, Anusol HC, Aquanil HC, Casporyn HC, Cipro, Cipro HC, Colocort, Cortaid, Cortane-B, Cortef, Cortenema, Cortisporin, Cortizone-10, Dermacort, Dermarest Eczema, Dermazene, Home Papkit, Hydroskin, Monistat Itch Relief, Neosporin Eczema, Preparation H Hydrocortisone, Procto-med, Procto-pak, Proctocort, Proctol, Proctosedyl, Proctosol, Proctozone HC, Scalpicin Itch Relief, Texacort, Vanoxide-HC, Xerese, Plenadren, Efmody
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O5
- CAS Number
- 50-23-7
- Unique Ingredient Identifier
- WI4X0X7BPJ
- Background
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Hydrocortisone was granted FDA approval on 5 August 1952.
- Indication
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated fo...
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Adrenal Insufficiency, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dermatitis, Dermatomyositis (DM), Dermatosis, Drug hypersensitivity reaction, Epicondylitis, Erythroblastopenia, Fissure;Anal, Haemorrhoids, Herpes Labialis, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Infection of the Fenestration Cavity, Infection of the Mastoidectomy Cavity, Iridocyclitis, Iritis, Itching caused by Hemorrhoids, Itching of the Anus, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Lymphomas NEC, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Hemorrhoids, Pemphigus, Posterior Uveitis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Proctitis, Proteinuria, Pruritis of the skin, Psoriatic Arthritis, Rectal inflammations NEC, Rheumatic heart disease, unspecified, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Skin Diseases, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Cryptitis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Superficial infection of the external auditory canal with inflammation, Symptomatic Sarcoidosis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
FDA Approves New Treatment for Congenital Adrenal Hyperplasia
FDA approved Crenessity (crinecerfont) with glucocorticoids to control androgen levels in adults and pediatric patients (4+ years) with classic congenital adrenal hyperplasia (CAH). Trials showed Crenessity reduced glucocorticoid doses by 27% in adults and 18% in children while maintaining androstenedione control. Common side effects include fatigue, dizziness, and joint pain. Crenessity has Fast Track, Breakthrough Therapy, Orphan Drug, and Priority Review designations.
The Hormonal Blueprint For Longevity: Unlocking Eternal Youthfulness
Hormones are crucial for longevity, influencing healthspan and aging processes. Key hormones include Growth Hormone, Sex Hormones, Cortisol, Insulin, and Melatonin, each affecting various aspects of health. Lifestyle factors like nutrition, exercise, and stress management support hormonal health. Innovations in hormonal health, such as personalized hormone replacement therapies and epigenetics modulation, are making longevity solutions more accessible. Hormonal balance, rooted in lifestyle and supported by precision medicine, is pivotal for extended vitality and resilience.
Precision One Health Symposium highlights successes
UGA's Precision One Health Symposium showcased interdisciplinary research on genetics, environment, and lifestyle's impact on disease, with nearly 24 faculty members and $10 million in funding.
Good Night's Sleep Wards Off High Blood Pressure in Teens
Research in the Journal of the American Heart Association shows that 9-11 hours of sleep nightly reduces teens' odds of high blood pressure by 37%.
Dr. Sara Szal Gottfried Explains the Health Impacts of All the Anger You're Feeling
Dr. Sara Szal Gottfried explains that stress responses like anxiety and anger can impact health if chronic, leading to issues like disrupted circadian rhythms, insomnia, and increased risk of heart attack. She suggests managing these emotions through awareness, controlled breathing, and meditation, while also recommending lifestyle changes such as reducing caffeine and alcohol intake.
Corcept Therapeutics Announces Third Quarter Financial Results, Positive Results
Corcept Therapeutics reports Q3 2024 revenue of $182.5M, up 48% YoY, and increases 2024 revenue guidance to $675-$700M. Net income per share is $0.41 (diluted), with cash and investments at $547.6M. The company plans to submit an NDA for relacorilant this quarter, supported by Phase 3 GRADIENT trial results.
Home-ics: how experiences of the home impact biology and child neurodevelopmental outcomes
Article references explore socioeconomic impacts on child development, brain structure, and neurodevelopmental outcomes, emphasizing the role of early life stress, parenting behavior, and neighborhood conditions in shaping cognitive and emotional outcomes.
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.
© Copyright 2024. All Rights Reserved by MedPath