Hydrocortisone
- Generic Name
- Hydrocortisone
- Brand Names
- Ala-cort, Ala-scalp, Alcortin, Alkindi, Anusol HC, Aquanil HC, Casporyn HC, Cipro, Cipro HC, Colocort, Cortaid, Cortane-B, Cortef, Cortenema, Cortisporin, Cortizone-10, Dermacort, Dermarest Eczema, Dermazene, Home Papkit, Hydroskin, Monistat Itch Relief, Neosporin Eczema, Preparation H Hydrocortisone, Procto-med, Procto-pak, Proctocort, Proctol, Proctosedyl, Proctosol, Proctozone HC, Scalpicin Itch Relief, Texacort, Vanoxide-HC, Xerese, Plenadren, Efmody
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O5
- CAS Number
- 50-23-7
- Unique Ingredient Identifier
- WI4X0X7BPJ
- Background
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Hydrocortisone was granted FDA approval on 5 August 1952.
- Indication
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated fo...
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Adrenal Insufficiency, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dermatitis, Dermatomyositis (DM), Dermatosis, Drug hypersensitivity reaction, Epicondylitis, Erythroblastopenia, Fissure;Anal, Haemorrhoids, Herpes Labialis, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Infection of the Fenestration Cavity, Infection of the Mastoidectomy Cavity, Iridocyclitis, Iritis, Itching caused by Hemorrhoids, Itching of the Anus, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Lymphomas NEC, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Hemorrhoids, Pemphigus, Posterior Uveitis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Proctitis, Proteinuria, Pruritis of the skin, Psoriatic Arthritis, Rectal inflammations NEC, Rheumatic heart disease, unspecified, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Skin Diseases, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Cryptitis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Superficial infection of the external auditory canal with inflammation, Symptomatic Sarcoidosis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)
- Conditions
- Interventions
- First Posted Date
- 2022-12-29
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- Agnes
- Target Recruit Count
- 30
- Registration Number
- NCT05668455
- Locations
- 🇫🇷
Centre Hospitalier Universitaire de Rennes _ Pontchaillou, Rennes, France
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
- Conditions
- Interventions
- First Posted Date
- 2022-07-27
- Last Posted Date
- 2024-12-06
- Target Recruit Count
- 54
- Registration Number
- NCT05476770
- Locations
- 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸Children's Hospital Orange County, Orange, California, United States
🇺🇸UCSF School of Medicine, San Francisco, California, United States
Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis
- First Posted Date
- 2022-06-29
- Last Posted Date
- 2024-10-26
- Target Recruit Count
- 600
- Registration Number
- NCT05436535
- Locations
- 🇺🇸
Children's Hospital Los Angeles: Division of Clinical Immunology & Allergy, Los Angeles, California, United States
🇺🇸University of Pennsylvania, Perelman Center for Advanced Medicine: Department of Dermatology, Philadelphia, Pennsylvania, United States
🇺🇸North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology, Chapel Hill, North Carolina, United States
Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
- Conditions
- Interventions
- First Posted Date
- 2022-06-28
- Last Posted Date
- 2022-06-28
- Lead Sponsor
- Ulla Feldt-Rasmussen
- Target Recruit Count
- 250
- Registration Number
- NCT05435781
- Locations
- 🇩🇰
Department of Endocrinology, Aarhus University Hospital, Aarhus, Denmark
🇩🇰Department of Endocrinology, Odense University Hospital, Odense, Denmark
🇩🇰Department of Medical Endocrinology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
HYDROcortisone Versus Placebo for Severe HospItal-acquired Pneumonia in Intensive Care Patients: the HYDRO-SHIP Study
- Conditions
- Interventions
- First Posted Date
- 2022-04-29
- Last Posted Date
- 2024-01-19
- Target Recruit Count
- 180
- Registration Number
- NCT05354778
- Locations
- 🇧🇷
Hospital do Servidor Publico Estadual, Sao Paulo, Sao Paulo SP, Brazil
Tacrolimus Versus Hydrocortisone in Atopic Dermatitis
- First Posted Date
- 2022-04-12
- Last Posted Date
- 2023-07-24
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 200
- Registration Number
- NCT05324618
- Locations
- 🇪🇬
Dermatology Clinic of National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt
Venetoclax Basket Trial for High Risk Hematologic Malignancies
- Conditions
- Myelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously TreatedTreatment-Related Acute Myeloid LeukemiaTherapy-Related Myelodysplastic SyndromeAcute Lymphoblastic Leukemia With Failed RemissionMyelodysplastic Syndromes, de NovoLymphoblastic Lymphoma, in RelapseAcute Leukemia of Ambiguous Lineage in RelapseLymphoblastic Lymphoma, RefractoryAcute Leukemia of Ambiguous Lineage
- Interventions
- First Posted Date
- 2022-03-23
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Andrew E. Place, MD
- Target Recruit Count
- 92
- Registration Number
- NCT05292664
- Locations
- 🇺🇸
University of California San Francisco-Benioff Children's Hospital, San Francisco, California, United States
🇺🇸Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment
- First Posted Date
- 2022-01-14
- Last Posted Date
- 2024-02-12
- Lead Sponsor
- Marianne Andersen
- Target Recruit Count
- 100
- Registration Number
- NCT05193396
- Locations
- 🇩🇰
OdenseUH, Odense, Denmark
Corticosteroids to Treat Pancreatitis
- Conditions
- Interventions
- First Posted Date
- 2021-12-16
- Last Posted Date
- 2024-08-12
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 86
- Registration Number
- NCT05160506
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia
- First Posted Date
- 2021-10-01
- Last Posted Date
- 2024-03-19
- Lead Sponsor
- Diurnal Limited
- Target Recruit Count
- 55
- Registration Number
- NCT05063994
- Locations
- 🇫🇷
Diurnal Investigational Site in Paris, Paris, France
🇺🇸Diurnal Investigational Site in Maryland, Bethesda, Maryland, United States
🇺🇸Diurnal Investigational Site in Rochester, Rochester, Minnesota, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.