Hydrocortisone
- Generic Name
- Hydrocortisone
- Brand Names
- Ala-cort, Ala-scalp, Alcortin, Alkindi, Anusol HC, Aquanil HC, Casporyn HC, Cipro, Cipro HC, Colocort, Cortaid, Cortane-B, Cortef, Cortenema, Cortisporin, Cortizone-10, Dermacort, Dermarest Eczema, Dermazene, Home Papkit, Hydroskin, Monistat Itch Relief, Neosporin Eczema, Preparation H Hydrocortisone, Procto-med, Procto-pak, Proctocort, Proctol, Proctosedyl, Proctosol, Proctozone HC, Scalpicin Itch Relief, Texacort, Vanoxide-HC, Xerese, Plenadren, Efmody
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O5
- CAS Number
- 50-23-7
- Unique Ingredient Identifier
- WI4X0X7BPJ
- Background
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Hydrocortisone was granted FDA approval on 5 August 1952.
- Indication
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated fo...
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Adrenal Insufficiency, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dermatitis, Dermatomyositis (DM), Dermatosis, Drug hypersensitivity reaction, Epicondylitis, Erythroblastopenia, Fissure;Anal, Haemorrhoids, Herpes Labialis, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Infection of the Fenestration Cavity, Infection of the Mastoidectomy Cavity, Iridocyclitis, Iritis, Itching caused by Hemorrhoids, Itching of the Anus, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Lymphomas NEC, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Hemorrhoids, Pemphigus, Posterior Uveitis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Proctitis, Proteinuria, Pruritis of the skin, Psoriatic Arthritis, Rectal inflammations NEC, Rheumatic heart disease, unspecified, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Skin Diseases, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Cryptitis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Superficial infection of the external auditory canal with inflammation, Symptomatic Sarcoidosis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock Patients
- First Posted Date
- 2018-10-18
- Last Posted Date
- 2021-05-20
- Lead Sponsor
- University of Tennessee Medical Center
- Target Recruit Count
- 84
- Registration Number
- NCT03710187
- Locations
- 🇺🇸
University of Tennessee Medical Center, Knoxville, Tennessee, United States
Post-operative Corticosteroid Treatment After Mitral Valve Surgery
- First Posted Date
- 2018-09-24
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Kuopio University Hospital
- Registration Number
- NCT03682393
- Locations
- 🇫🇮
Kuopio University Hospital, Kuopio, Finland
Investigation of Nicotine Seeking Behavior in Current Smokers
- Conditions
- Interventions
- First Posted Date
- 2018-09-13
- Last Posted Date
- 2018-09-13
- Lead Sponsor
- Wayne State University
- Target Recruit Count
- 21
- Registration Number
- NCT03670212
- Locations
- 🇺🇸
Wayne State University, Detroit, Michigan, United States
Thiamine As An Adjuvant Therapy For Hyperlactatemia In Septic Shock Patients
- Conditions
- Interventions
- First Posted Date
- 2018-08-28
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
- Target Recruit Count
- 72
- Registration Number
- NCT03649009
- Locations
- 🇲🇾
Universiti Kebangsaan Malaysia Medical Centre, Cheras, Kuala Lumpur, Malaysia
Ramadan Fasting in Patients With Corticotrope Deficiency Treated Either by Hydrocortisone or by Prednisolone
- Conditions
- Interventions
- First Posted Date
- 2018-07-13
- Last Posted Date
- 2019-04-29
- Lead Sponsor
- University Tunis El Manar
- Target Recruit Count
- 53
- Registration Number
- NCT03585829
- Locations
- 🇹🇳
University Tunis El Manar, Tunis, Tunisia
Patient Self-administration of Cortisol for Cortisol-responding Disorders in Men and Women Over the Age of 17
- First Posted Date
- 2018-06-15
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Helen Foundation
- Target Recruit Count
- 2430
- Registration Number
- NCT03558971
- Locations
- 🇺🇸
Helen Foundation Clinic, Apache Junction, Arizona, United States
Androgen Reduction in Congenital Adrenal Hyperplasia
- Conditions
- Interventions
- First Posted Date
- 2018-06-07
- Last Posted Date
- 2023-02-01
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Registration Number
- NCT03548246
- Locations
- 🇺🇸
Children's Medical Center, Dallas, Texas, United States
🇺🇸Children's Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸National Institutes of Health, Bethesda, Maryland, United States
Vitamin C, Thiamine, and Steroids in Sepsis
- Conditions
- Interventions
- First Posted Date
- 2018-04-26
- Last Posted Date
- 2021-04-13
- Lead Sponsor
- Emory University
- Target Recruit Count
- 501
- Registration Number
- NCT03509350
- Locations
- 🇺🇸
University of Arizona, Tucson, Arizona, United States
🇺🇸Yale New Haven Hospital, New Haven, Connecticut, United States
🇺🇸Christiana Care, Newark, Delaware, United States
Steroids on Intra-dialytic Hypotension
- Conditions
- Interventions
- First Posted Date
- 2018-03-14
- Last Posted Date
- 2019-04-08
- Lead Sponsor
- University of Jordan
- Target Recruit Count
- 82
- Registration Number
- NCT03465007
- Locations
- 🇯🇴
School of Medicine, Amman, Jordan
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
- Conditions
- Interventions
- First Posted Date
- 2018-02-05
- Last Posted Date
- 2021-09-21
- Lead Sponsor
- Community Medical Center, Toms River, NJ
- Target Recruit Count
- 140
- Registration Number
- NCT03422159
- Locations
- 🇺🇸
Community Medical Center, Toms River, New Jersey, United States
🇺🇸Monmouth Medical Center, Southern Campus, Lakewood, New Jersey, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.