Bethanechol

Generic Name
Bethanechol
Brand Names
Duvoid
Drug Type
Small Molecule
Chemical Formula
C7H17N2O2
CAS Number
674-38-4
Unique Ingredient Identifier
004F72P8F4
Background

Bethanechol is a synthetic ester that was initially synthesized in 1935. As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary. For example, bethanechol is readily used to treat postoperative or postpartum urin...

Indication

Bethanechol is indicated for the treatment of acute, functional postpartum and postoperative urinary retention. It is also indicated for the treatment of neurogenic atony of the bladder with retention.

Associated Conditions
Acute post-operative Urinary retention, Neurogenic atony of the urinary bladder, Non-obstructive postpartum urinary retention
Associated Therapies
-

The Effect of Bethanechol on Tracheobronchomalacia

Recruiting
Conditions
Interventions
First Posted Date
2022-03-28
Last Posted Date
2024-01-30
Lead Sponsor
Arkansas Children's Hospital Research Institute
Target Recruit Count
20
Registration Number
NCT05299008
Locations
🇺🇸

Arkansas Children's Hospital, Little Rock, Arkansas, United States

Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma

First Posted Date
2022-02-15
Last Posted Date
2024-03-05
Lead Sponsor
Susan E. Bates
Target Recruit Count
37
Registration Number
NCT05241249
Locations
🇺🇸

Columbia University Medical Center, New York, New York, United States

Bethanechol Prior to Pancreatic Surgery

Early Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-06-28
Last Posted Date
2024-08-21
Lead Sponsor
Columbia University
Target Recruit Count
17
Registration Number
NCT03572283
Locations
🇺🇸

Columbia University Medical Center, New York, New York, United States

Bethanechol for Eosinophilic Esophagitis

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2014-02-10
Last Posted Date
2016-04-22
Lead Sponsor
University of Iowa
Target Recruit Count
2
Registration Number
NCT02058537
Locations
🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

Topical Bethanechol for Improvement of Esophageal Dysmotility

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-12-14
Last Posted Date
2015-01-29
Lead Sponsor
Augusta University
Target Recruit Count
5
Registration Number
NCT01031043
Locations
🇺🇸

Medical College of Georgia, Augusta, Georgia, United States

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