Tafenoquine
- Generic Name
- Tafenoquine
- Brand Names
- Arakoda, Krintafel
- Drug Type
- Small Molecule
- Chemical Formula
- C24H28F3N3O3
- CAS Number
- 106635-80-7
- Unique Ingredient Identifier
- 262P8GS9L9
- Background
Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group. It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria. Tafenoquine was further developed collaboratively between Glaxo...
- Indication
用于16岁及以上疟疾患者，根治(预防复发)由间日疟原虫(P.vivax)导致的疟疾。
- Associated Conditions
- Malaria caused by plasmodium vivax
- Associated Therapies
- -
G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine)
- First Posted Date
- 2010-09-20
- Last Posted Date
- 2017-06-07
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 192
- Registration Number
- NCT01205178
- Locations
- 🇹🇭
GSK Investigational Site, Tak, Thailand
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