Memantine
- Generic Name
- Memantine
- Brand Names
- Axura, Ebixa, Marixino, Namenda, Namenda 49 Titration Pack, Namzaric, Nemdatine, Memantine Mylan, Memantine ratiopharm, Memantine Merz, Marixino (previously Maruxa), Memantine Accord, Memantine LEK
- Drug Type
- Small Molecule
- Chemical Formula
- C12H21N
- CAS Number
- 19982-08-2
- Unique Ingredient Identifier
- W8O17SJF3T
- Background
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease . ...
- Indication
Memantine is used to manage moderate to severe Alzheimer's dementia .
...
- Associated Conditions
- Alzheimer's Disease (AD), Moderate to Severe Alzheimer's Disease, Mild Vascular dementia, Moderate Alzheimer's Type Dementia, Moderate Vascular dementia, Severe Alzheimer's Type Dementia
- Associated Therapies
- -
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
- First Posted Date
- 2024-12-11
- Last Posted Date
- 2024-12-11
- Lead Sponsor
- UNC Lineberger Comprehensive Cancer Center
- Target Recruit Count
- 90
- Registration Number
- NCT06727773
- Locations
- 🇺🇸
Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, United States
Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury
- Conditions
- Interventions
- First Posted Date
- 2024-03-29
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT06337994
- Locations
- 🇪🇬
Assiut University, Faculty of Medicine, Hospital of Neurology, Psychiatry and Neurosurgery, Assiut, Egypt
A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer
- First Posted Date
- 2023-08-23
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- Inova Health Care Services
- Target Recruit Count
- 12
- Registration Number
- NCT06007846
- Locations
- 🇺🇸
Inova Health Care Service, Falls Church, Virginia, United States
🇺🇸Inova Schar Cancer Institute, Fairfax, Virginia, United States
Efficacy of Memantine in Prevention of Oxaliplatin-induced Peripheral Neurotoxicity
- First Posted Date
- 2023-04-28
- Last Posted Date
- 2023-04-28
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 60
- Registration Number
- NCT05834231
Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors
- Conditions
- Interventions
- First Posted Date
- 2023-04-03
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 28
- Registration Number
- NCT05796752
- Locations
- 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States
Glutamate Inhibitors in Glioblastoma
- Conditions
- Interventions
- First Posted Date
- 2022-12-23
- Last Posted Date
- 2024-05-10
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 120
- Registration Number
- NCT05664464
- Locations
- 🇨🇭
University Hospital Zurich, Zürich, Zurich, Switzerland
Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2022-09-14
- Last Posted Date
- 2022-09-14
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 180
- Registration Number
- NCT05538507
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, China
Effect of Early Memantine Administration on Outcome of Patients With Moderate to Severe Traumatic Brain Injury
- Conditions
- Interventions
- First Posted Date
- 2022-09-08
- Last Posted Date
- 2022-09-08
- Lead Sponsor
- Minia University
- Target Recruit Count
- 70
- Registration Number
- NCT05531383
- Locations
- 🇪🇬
Faculty of medecine, Minya, Minia, Egypt
Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge
- Conditions
- Interventions
- First Posted Date
- 2022-06-14
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 45
- Registration Number
- NCT05418049
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
The Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2021-11-01
- Last Posted Date
- 2021-11-01
- Lead Sponsor
- Istanbul Medipol University Hospital
- Target Recruit Count
- 27
- Registration Number
- NCT05102045
- Locations
- 🇹🇷
Istanbul Medipol University, İstanbul, Beykoz, Turkey
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.