MedPath

Capivasertib

Generic Name
Capivasertib
Brand Names
Truqap
Drug Type
Small Molecule
Chemical Formula
C21H25ClN6O2
CAS Number
1143532-39-1
Unique Ingredient Identifier
WFR23M21IE
Background

Capivasertib has been investigated for the treatment of Metastatic Breast Cancer.

Associated Conditions
-
Associated Therapies
-

Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Phase 2
Active, not recruiting
Conditions
Endometrioid Adenocarcinoma
Stage IV Uterine Corpus Cancer AJCC v8
Endometrial Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Interventions
Procedure: Biospecimen Collection
Procedure: Bone Marrow Aspirate
Procedure: Bone Marrow Biopsy
Drug: Cediranib
Drug: Capivasertib
Drug: Cediranib Maleate
Biological: Durvalumab
Procedure: Computed Tomography
Procedure: Echocardiography
Drug: Olaparib
Procedure: Multigated Acquisition Scan
First Posted Date
2018-09-07
Last Posted Date
2025-01-06
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
288
Registration Number
NCT03660826
Locations
🇺🇸

Jupiter Medical Center, Jupiter, Florida, United States

🇺🇸

Sacred Heart Hospital, Pensacola, Florida, United States

🇺🇸

Florida Cancer Specialists - Sarasota, Sarasota, Florida, United States

and more 764 locations
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