Amsacrine
- Generic Name
- Amsacrine
- Drug Type
- Small Molecule
- Chemical Formula
- C21H19N3O3S
- CAS Number
- 51264-14-3
- Unique Ingredient Identifier
- 00DPD30SOY
Overview
Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Background
Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Indication
For treatment of acute myeloid leukaemia.
Associated Conditions
- Refractory Leukemia
Clinical Trials
FDA Approved Products
Singapore Approved Products
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