PX-478
- Generic Name
- PX-478
- Drug Type
- Small Molecule
- Chemical Formula
- C13H20Cl4N2O3
- CAS Number
- 685898-44-6
- Unique Ingredient Identifier
- T23U22X160
Overview
PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha.
Background
PX-478 is a small molecule inhibitor of hypoxia inducible factor (HIF)-1 alpha currently in a clinical trial in patients with advanced metastatic cancer and lymphoma. PX-478 was effective in models of both non-small cell lung cancer and small cell lung cancer that express HIF-1 alpha.
Indication
Investigated for use/treatment in cancer/tumors (unspecified).
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2007/08/30 | Phase 1 | Completed |
FDA Approved Products
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No FDA products found
No FDA products found for this drug
EMA Approved Products
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No EMA products found
No EMA products found for this drug
Singapore Approved Products
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No Singapore products found
No Singapore products found for this drug
China Approved Products
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No China products found
No China products found for this drug
Australia Approved Products
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No Australia products found
No Australia products found for this drug