Toripalimab

Generic Name
Toripalimab
Brand Names
Loqtorzi
Drug Type
Biotech
Chemical Formula
-
CAS Number
1924598-82-2
Unique Ingredient Identifier
8JXN261VVA
Background

Toripalimab is under investigation in clinical trial NCT03919383 (Phase II of Lenvatinib Plus Toripalimab for Advanced HCC).

Indication

⑴用于治疗既往标准治疗失败后的局部进展或转移性黑色素瘤。⑵用于治疗既往接受过二线及以上系统治疗失败的复发/转移性鼻咽癌(NPC)。⑶用于治疗既往接受过治疗的局部进展或转移性尿路上皮癌(UC)。⑷用于食管鳞癌一线治疗。

Associated Conditions
-
Associated Therapies
-

A Study of WX390 Combined With Toripalimab in Patients With Advanced Gastric-type Endocervical Adenocarcinoma With STK11 Mutations

First Posted Date
2023-11-09
Last Posted Date
2024-12-10
Lead Sponsor
Shanghai Jiatan Pharmatech Co., Ltd
Target Recruit Count
20
Registration Number
NCT06124963
Locations
🇨🇳

The Obstetrics & Gynecology Hospital of Fudan University (Shanghai Red House Ob & Gyn Hospital), Shanghai, Shanghai, China

A Study of WX390 Combined With Toripalimab in Patients With Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-11-07
Last Posted Date
2024-11-25
Lead Sponsor
Shanghai Jiatan Pharmatech Co., Ltd
Target Recruit Count
100
Registration Number
NCT06117566
Locations
🇨🇳

the first affiliated hospital of Jilin university, Changchun, Jilin, China

Neoadjuvant Immune-based Combinations in Patients Undergoing Nephrectomy for Locally Advanced ccRCC

First Posted Date
2023-11-02
Last Posted Date
2024-04-26
Lead Sponsor
Jinling Hospital, China
Target Recruit Count
32
Registration Number
NCT06114940
Locations
🇨🇳

Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China, Nanjing, Jiangsu, China

Study of Disitamab Vedotin With Toripalimab Verus Disitamab Vedotin in Hormone Receptor Positive, HER2-low Locally Advanced or Metastatic Breast Cancer

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2023-10-27
Last Posted Date
2024-08-23
Lead Sponsor
RemeGen Co., Ltd.
Registration Number
NCT06105008
Locations
🇨🇳

Jiangsu Provincial People's Hospital, Nanjing, Jiangsu, China

🇨🇳

Binghe Xu, Beijing, Cancer Hospital Chinese Academy Of Medical Sciences, China

🇨🇳

Hunan Cancer Hospital, Changsha, China

Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer

First Posted Date
2023-10-23
Last Posted Date
2023-10-23
Lead Sponsor
Tianjin Medical University Cancer Institute and Hospital
Target Recruit Count
20
Registration Number
NCT06093438
Locations
🇨🇳

Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin, China

Phase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 in Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-10-18
Last Posted Date
2024-10-30
Lead Sponsor
Suzhou Abogen Biosciences Co., Ltd.
Target Recruit Count
218
Registration Number
NCT06088004
Locations
🇨🇳

Guangxi Medical University Cancer Hospital, Nanning, China

🇨🇳

Cancer Hospital Chinese Academy of Medical Sciences, Beijing, China

🇨🇳

Sun Yat-sen University Cancer Center, Guangzhou, China

and more 2 locations

Toripalimab in Combined With Cetuximab,Chemotherapy for Conversion Therapy of Locally Nonresectable OCSCC

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-10-13
Last Posted Date
2023-10-13
Lead Sponsor
First Affiliated Hospital of Zhejiang University
Target Recruit Count
33
Registration Number
NCT06081582
Locations
🇨🇳

Department of Medical Onocology, First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China

AG Combined With Immunotherapy and SBRT in Patients With Potentially Resectable Pancreatic Cancer

First Posted Date
2023-10-12
Last Posted Date
2023-10-12
Lead Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Target Recruit Count
108
Registration Number
NCT06080854
Locations
🇨🇳

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China

9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial Cancer

Phase 1
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-10-12
Last Posted Date
2023-10-12
Lead Sponsor
Mabwell (Shanghai) Bioscience Co., Ltd.
Target Recruit Count
100
Registration Number
NCT06079112
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

Posterior-line Treatment With Disitamab Vedotin Plus PD-1 in Advanced HER2-low Expressing Gastric Cancer

First Posted Date
2023-10-12
Last Posted Date
2023-10-12
Lead Sponsor
Shanghai East Hospital
Target Recruit Count
39
Registration Number
NCT06078982
Locations
🇨🇳

Shanghai East Hospital, Shanghai, China

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