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Riltozinameran is a component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineage BA.1.
Riltozinameran is a component of a bivalent COVID-19 mRNA vaccine encoding the viral spike protein of Omicron variant lineage BA.1.
Riltozinameran is a nucleoside-modified mRNA encapsulated in lipid nanoparticles that facilitate the delivery of the mRNA into human cells. Once inside the host cells, the mRNA is translated by host machinery to produce a modified SARS-CoV-2 spike (S) protein - specifically the S protein of the Omicron BA.1 variant lineage - which is subsequently recognized by the host immune system. Both neutralizing antibody and cellular immune responses are elicited in response to the vaccine, which helps protect against SARS-CoV-2 infection.
Riltozinameran, in combination with tozinameran (Comirnaty Original / Omicron BA.1), is indicated in patients ≥12 years of age as a booster dose for active immunization against COVID-19 caused by SARS-CoV-2. It may be given 3 to 6 months after completion of a primary course of Comirnaty and/or a previous booster dose of Comirnaty.
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