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Hydrochlorothiazide

Generic Name
Hydrochlorothiazide
Brand Names
Accuretic, Actelsar Hct, Aldactazide, Altace HCT, Atacand, Atacand Hct, Avalide, Benicar Hct, Diovan Hct, Exforge Hct, Hyzaar, Ifirmacombi, Karvezide, Lopressor Hct, Lotensin Hct, Maxzide, Micardis-hct, Olmetec Plus, Tekturna Hct, Teveten HCT, Tribenzor, Urozide, Vaseretic, Viskazide, Zestoretic, Ziac
Drug Type
Small Molecule
Chemical Formula
C7H8ClN3O4S2
CAS Number
58-93-5
Unique Ingredient Identifier
0J48LPH2TH

Overview

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors or angiotensin II receptor blockers. Hydrochlorothiazide was granted FDA approval on 12 February 1959.

Background

Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension. Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors or angiotensin II receptor blockers. Hydrochlorothiazide was granted FDA approval on 12 February 1959.

Indication

Hydrochlorothiazide is indicated alone or in combination for the management of edema associated with congestive heart failure, hepatic cirrhosis, nephrotic syndrome, acute glomerulonephritis, chronic renal failure, and corticosteroid and estrogen therapy. Hydrochlorothiazide is also indicated alone or in combination for the management of hypertension.

Associated Conditions

  • Calcium Nephrolithiasis
  • Cirrhosis of the Liver
  • Congestive Heart Failure (CHF)
  • Diabetes Insipidus
  • Edema
  • Hypertension
  • Hypertension, Essential Hypertension
  • Hypokalemia caused by diuretics
  • Nephrotic Syndrome
  • Pre-Eclampsia
  • Premenstrual tension with edema
  • Renal tubular acidosis
  • Sodium retention
  • Stroke

FDA Approved Products

Hydrochlorothiazide
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:25 mg in 1 1
Approved: 2017/02/21
NDC:71335-1481
Lisinopril and Hydrochlorothiazide
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:25 mg in 1 1
Approved: 2020/01/13
NDC:71610-383
Lisinopril and Hydrochlorothiazide
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:12.5 mg in 1 1
Approved: 2020/01/13
NDC:71610-374
Lisinopril and Hydrochlorothiazide
Manufacturer:LUPIN LIMITED
Route:ORAL
Strength:25 mg in 1 1
Approved: 2016/05/09
NDC:57297-520
Bisoprolol Fumarate and Hydrochlorothiazide
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:6.25 mg in 1 1
Approved: 2022/02/04
NDC:50090-6413

Singapore Approved Products

No Singapore products found for this drug

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