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NIO-752

Generic Name
NIO-752

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK

Phase 1
Not yet recruiting
Conditions
Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder)
Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder)
Alzheimer Disease
Interventions
Other: Placebo
First Posted Date
2024-04-18
Last Posted Date
2024-04-18
Lead Sponsor
University College, London
Target Recruit Count
10
Registration Number
NCT06372821

Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants

Phase 1
Recruiting
Conditions
Mild Cognitive Impairment
Alzheimer Disease
Interventions
Drug: Matching placebo
First Posted Date
2022-07-21
Last Posted Date
2025-04-29
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
36
Registration Number
NCT05469360
Locations
🇸🇪

Novartis Investigative Site, Stockholm, Sweden

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