Pyrimethamine
- Generic Name
- Pyrimethamine
- Brand Names
- Daraprim
- Drug Type
- Small Molecule
- Chemical Formula
- C12H13ClN4
- CAS Number
- 58-14-0
- Unique Ingredient Identifier
- Z3614QOX8W
- Background
One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
- Indication
For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine
- Associated Conditions
- Toxoplasmosis
- Associated Therapies
- -
Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected Patients
Phase 2
Completed
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-02
- Target Recruit Count
- 150
- Registration Number
- NCT00000643
- Locations
- 🇺🇸
Harbor-UCLA Med. Ctr. CRS, Torrance, California, United States
🇺🇸Northwestern University CRS, Chicago, Illinois, United States
🇺🇸Rush Univ. Med. Ctr. ACTG CRS, Chicago, Illinois, United States
Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
Phase 4
Recruiting
- Conditions
- Interventions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2009-05-14
- Target Recruit Count
- 600
- Registration Number
- NCT00004317
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
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