Overview
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic nature . Chloroxylenol is on the World Health Organization's List of Essential Medicines.
Indication
The predominant medical applications for which chloroxylenol is formally indicated for therapeutic use is as an application to the skin for use in cuts, bites, stings, abrasions, and for use as antiseptic hand cleaner .
Associated Conditions
- Skin Infections
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| First Medical Infection Control Associates, Inc. | 68663-876 | TOPICAL | 3 mg in 1 mL | 4/22/2025 | |
| Pro Chem, Inc. | 63830-544 | TOPICAL | 3 mg in 1 mL | 4/22/2025 | |
| ABC Compounding Co., Inc. | 62257-161 | TOPICAL | 3 mg in 1 mL | 4/22/2025 | |
| Costco Wholesale Corporation | 63981-933 | TOPICAL | 3 mg in 1 mL | 3/31/2025 | |
| The Procter & Gamble Manufacturing Company | 84126-107 | TOPICAL | 0.35 g in 100 mL | 3/19/2025 | |
| ABC Compounding Co., Inc. | 62257-160 | TOPICAL | 3 mg in 1 mL | 4/22/2025 | |
| BLANSETT PHARMACAL CO | 51674-0117 | TOPICAL | 1 mg in 1 mL | 3/20/2017 | |
| Royal Paper Corp. | 59723-101 | TOPICAL | 1 g in 1 L | 8/22/2024 | |
| KYNC DESIGN LLC | 76557-050 | CUTANEOUS, TOPICAL | 0.2 g in 100 g | 5/20/2025 | |
| ABC Compounding Co., Inc. | 62257-875 | TOPICAL | 3 mg in 1 mL | 4/22/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| DETTOL ANTISEPTIC SOLUTION chloroxylenol 48 mg/mL bottle (reformulation) | 61404 | Medicine | A | 10/22/1997 | |
| Lisanol Antiseptic Chloroxylenol 50mg/mL solution bottle | 14705 | Medicine | A | 10/25/1991 | |
| DETTOL antiseptic cream tube | 15362 | Medicine | A | 9/30/1991 | |
| APURA PREPQARATION ANTIBACTERIAL CLEANSING GEL tube | 91424 | Medicine | A | 10/22/2002 | |
| WOOLWORTHS ESSENTIALS ANTISEPTIC SOLUTION chloroxylenol 48 mg/g bottle | 187463 | Medicine | A | 8/9/2011 | |
| COLES ANTISEPTIC SOLUTION chloroxylenol 4.8% w/w bottle | 28611 | Medicine | A | 11/1/1991 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| ANTIMICROBIAL LOTION CREAM SOAP | gojo industries, inc. | 02020351 | Soap Bar
,
Liquid - Topical | .6 % | 12/31/1993 |
| GERMICIDAL HAND SOAP LIQ 0.6% | ostrem chemical co ltd. | 01977873 | Liquid - Topical | 0.6 % | 12/31/1992 |
| FOAMING HAND WASH | cp industries ltd | 02366428 | Solution - Topical (Commercial) | 0.50 % | N/A |
| E-Z SCRUB ANTIMICROBIAL FOAM SOLUTION CONTAINING 3% PCMX | becton dickinson | 02241055 | Liquid - Topical | 3 % | 10/19/2000 |
| GARD 0.5% | avmor ltd | 00553557 | Liquid - Topical | .5 % | 12/31/1982 |
| ABSORBINE JR LINIMENT | bridges consumer healthcare llc | 01942301 | Solution - Topical | 0.5 % | 12/31/1993 |
| DETTOL LIQ 10% | safetex products ltd. | 00310999 | Liquid - Topical | 10 % | 12/31/1964 |
| ANTISEPTIC LOTION SOAP | inland/alcare | 00664529 | Soap Bar - Topical | 0.36 % | 12/31/1986 |
| ZETAR SHAMPOO | rhone-poulenc rorer consumer inc. | 01937642 | Shampoo
,
Liquid - Topical | 0.5 % | 12/31/1993 |
| VIONEXUS ANTIMICROBIAL FOAMING SOAP | metrex research, llc | 02244129 | Liquid - Topical | 1 % | 6/8/2001 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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