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Torasemide

Generic Name
Torasemide
Brand Names
Demadex, Soaanz
Drug Type
Small Molecule
Chemical Formula
C16H20N4O3S
CAS Number
56211-40-6
Unique Ingredient Identifier
W31X2H97FB
Background

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.

Indication

Torasemide is indicated for the treatment of edema associated with congestive heart failure, renal or hepatic diseases. From this condition, it has been observed that torasemide is very effective in cases of kidney failure.

As well, torasemide is approved to be used as an antihypertensive agent either alone or in combination with other antihypertensives.

Associated Conditions
Edema, Hypertension

Singapore Trial to Evaluate Multicomponent Intervention for Chronic Kidney Disease Management

• A new study will evaluate a multicomponent intervention (SKOPE) for managing kidney outcomes in patients with chronic kidney disease (CKD). • The SKOPE intervention includes training for nurses and physicians, regular case review meetings, and subsidies for SGLT2i medications. • The primary outcome will be the eGFR total slope from randomization to final follow-up at 36 months, with secondary outcomes including CVD risk score and quality of life. • The trial aims to determine if the SKOPE interventions can be adopted into clinical practice for patients with CKD, compared to usual care.
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