二氟泼尼酯 (Durezol)

概览

Difluprednate is a topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.

作用机制

Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins (lipocortins). It is postulated that these proteins control the biosynthesis of potent mediators of infammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.

适应症

For the treatment of inflammation and pain associated with ocular surgery.

• Anterior Uveitis (AU)
• Endogenous Anterior Uveitis
• Eye Pain
• Ocular Inflammation
• Pain of the eye