MedPath

Pholcodine

Generic Name
Pholcodine
Drug Type
Small Molecule
Chemical Formula
C23H30N2O4
CAS Number
509-67-1
Unique Ingredient Identifier
LPP64AWZ7L

Overview

Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little or no analgesic effects. Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. Pholcodine is not approved in Canada.

Background

Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little or no analgesic effects. Pholcodine is not prescribed in the United States where it is classed as a Schedule I drug. It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. Pholcodine is not approved in Canada.

Indication

Pholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough." Cough is the respiratory movement that occurs after an irritation signal is transmitted to the central nervous system and further stimulates the medulla oblongata. This stimulation causes a motor output that is sent through motoneurons to the respiratory muscles. A non-productive cough is a type of cough characterized by the absence of sputum, and it has a large inspiration that will cause continuous coughing.

Associated Conditions

  • Cough
  • Cough caused by Common Cold
  • Epiphora
  • Flu caused by Influenza
  • Irritative cough
  • Rhinorrhoea
  • Sinusitis
  • Sneezing
  • Throat irritation
  • Dry cough
  • Fever or influenza-like illness

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2022/08/15
Not Applicable
Completed
Shanghai Children's Medical Center

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code

No FDA products found

No FDA products found for this drug

EMA Approved Products

Medicine Name
EMA Number
Auth. Holder
Country
Drug Type
Status
Issued
Opinion
Revision

No EMA products found

No EMA products found for this drug

HSA Approved Products

Product Name
Manufacturer
Dosage Form
Strength
Approved
Approval No.

No HSA products found

No HSA products found for this drug

NMPA Approved Products

Product Name
Approval No.
Manufacturer
Dosage Form
Trade Name
Strength
Type
Status
Date
Import
国药准字H42022113
片剂
N/A
15mg
Chemical Drug
Approved
2020/07/16
Domestic
国药准字H42022286
片剂
N/A
5mg
Chemical Drug
Approved
2020/07/16
Domestic
国药准字H42022080
片剂
N/A
10mg
Chemical Drug
Approved
2020/07/16
Domestic

PPB Approved Products

Product Name
Registration Code
Company
Category
Sale Type
Reg. Date

No PPB products found

No PPB products found for this drug

TGA Approved Products

Product Name
ARTG ID
Sponsor
Status
Reg. Date
Ingredient

No TGA products found

No TGA products found for this drug

© Copyright 2025. All Rights Reserved by MedPath