MedPath

Nitric Oxide

Generic Name
Nitric Oxide
Brand Names
Inomax, Kinox, Noxivent, INOmax
Drug Type
Small Molecule
Chemical Formula
NO
CAS Number
10102-43-9
Unique Ingredient Identifier
31C4KY9ESH

Overview

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants. Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color.

Background

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants. Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color.

Indication

For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure

Associated Conditions

  • Hypoxic Respiratory Failure

FDA Approved Products

Ulspira
Manufacturer:Airgas Therapeutics, LLC
Route:RESPIRATORY (INHALATION)
Strength:0.8 mL in 100 L
Approved: 2023/11/30
NDC:82605-006
INOMAX
Manufacturer:INO THERAPEUTICS LLC
Route:RESPIRATORY (INHALATION)
Strength:6 mg in 1 L
Approved: 2023/04/12
NDC:64693-003
INOMAX
Manufacturer:INO THERAPEUTICS LLC
Route:RESPIRATORY (INHALATION)
Strength:0.98 mg in 1 L
Approved: 2023/04/12
NDC:64693-002
GENOSYL
Manufacturer:VERO BIOTECH, INC.
Route:RESPIRATORY (INHALATION)
Strength:0.98 mg in 1 L
Approved: 2022/12/01
NDC:72385-002
Noxivent 102
Manufacturer:Linde Gas & Equipment Inc
Route:RESPIRATORY (INHALATION)
Strength:800 mg in 1 L
Approved: 2023/01/19
NDC:59579-102

Singapore Approved Products

No Singapore products found for this drug

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