Paricalcitol

Generic Name
Paricalcitol
Brand Names
Zemplar
Drug Type
Small Molecule
Chemical Formula
C27H44O3
CAS Number
131918-61-1
Unique Ingredient Identifier
6702D36OG5
Background

Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.

Indication

For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4

Associated Conditions
Secondary Hyperparathyroidism (SHPT)
Associated Therapies
-

Oral Paricalcitol in Stage 3 - 5 Chronic Kidney Disease

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-11-24
Last Posted Date
2017-01-10
Lead Sponsor
The University of Hong Kong
Target Recruit Count
60
Registration Number
NCT00796679
Locations
🇭🇰

University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong

🇭🇰

Queen Mary Hospital, Hong Kong, Hong Kong

Vitamin D and Coronary Calcification Study

First Posted Date
2008-09-15
Last Posted Date
2017-12-08
Lead Sponsor
Joslin Diabetes Center
Target Recruit Count
44
Registration Number
NCT00752102
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Long-term Safety Study of Paricalcitol Injection in Chronic Kidney Disease Patients With Hemodialysis (HD)

First Posted Date
2008-06-19
Last Posted Date
2011-04-19
Lead Sponsor
Abbott
Target Recruit Count
107
Registration Number
NCT00701805

Immune Effects of Vitamin D in Hemodialysis Patients

First Posted Date
2008-05-30
Last Posted Date
2009-05-13
Lead Sponsor
Renal Research Institute
Target Recruit Count
20
Registration Number
NCT00686751
Locations
🇺🇸

Upper Manhattan Dialysis Center, New York, New York, United States

🇺🇸

Yorkville Dialysis Center, New York, New York, United States

🇺🇸

Irving Place Dialysis Center, New York, New York, United States

Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis

First Posted Date
2008-04-28
Last Posted Date
2012-01-20
Lead Sponsor
Abbott
Target Recruit Count
153
Registration Number
NCT00667576

Efficacy and Safety of Paricalcitol on the Treatment of Secondary Hyperparathyroidism in Calcitriol Resistant Dialysis Subjects

First Posted Date
2008-04-23
Last Posted Date
2012-01-20
Lead Sponsor
Abbott
Target Recruit Count
13
Registration Number
NCT00664430
Locations
🇧🇷

Site Reference ID/Investigator# 7118, Sao Paulo, Brazil

🇧🇷

Site Reference ID/Investigator# 7114, Sao Paulo, Brazil

Paricalcitol Injection Phase II Trial

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-03-31
Last Posted Date
2008-03-31
Lead Sponsor
Abbott
Target Recruit Count
25
Registration Number
NCT00646932

Paricalcitol and Chemotherapy in Treating Women With Metastatic Breast Cancer

First Posted Date
2008-03-18
Last Posted Date
2017-05-30
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
24
Registration Number
NCT00637897
Locations
🇺🇸

Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

Paricalcitol in Treating Patients With Advanced Prostate Cancer and Bone Metastases

Phase 2
Terminated
Conditions
First Posted Date
2008-03-13
Last Posted Date
2018-07-06
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
2
Registration Number
NCT00634582
Locations
🇺🇸

Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

Paricalcitol for the Treatment of Immunoglobulin A Nephropathy

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2008-01-24
Last Posted Date
2015-08-03
Lead Sponsor
Chinese University of Hong Kong
Registration Number
NCT00599963
Locations
🇭🇰

Department of Medicine & Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong

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