Overview
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization. Research indicates that parental exposure to phenol and its related compounds are positively associated with spontaneous abortion. During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.
Indication
Phenol is primarily indicated for minor sore throat pain, sore mouth, minor mouth irritation, and pain associated with canker sores. Additionally, phenol is indicated in the treatment of focal spasticity.
Associated Conditions
- Atopic Dermatitis
- Dermatitis
- Irritation lips
- Pruritis of the skin
- Psoriasis
- Ringworm
- Sore Throat
- Throat irritation
- Moderate, stable Psoriasis
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/06/17 | Not Applicable | Recruiting | Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital | ||
2025/06/15 | Not Applicable | Not yet recruiting | |||
2024/02/20 | Not Applicable | Recruiting | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital | ||
2023/08/21 | Phase 4 | Not yet recruiting | |||
2021/08/04 | Phase 4 | UNKNOWN | Kessler Foundation | ||
2021/03/12 | Early Phase 1 | Active, not recruiting | Our Lady of the Lake Hospital | ||
2020/12/23 | Phase 4 | Completed | Gulhane Training and Research Hospital | ||
2020/09/23 | Phase 4 | Completed | Umraniye Education and Research Hospital | ||
2019/06/04 | Phase 4 | Withdrawn | |||
2018/07/26 | Not Applicable | UNKNOWN | Federal University of São Paulo |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Peaceful Mountain, Inc. | 43846-0017 | TOPICAL | 30 [hp_X] in 1 g | 5/21/2025 | |
| Antigen Laboratories, Inc. | 49288-9932 | INTRADERMAL, SUBCUTANEOUS | 0.004 mL in 1 mL | 12/8/2009 | |
| Deseret Biologicals, Inc. | 43742-2108 | ORAL | 12 [hp_X] in 1 mL | 5/27/2025 | |
| Antigen Laboratories, Inc. | 49288-9936 | INTRADERMAL, SUBCUTANEOUS | 0.004 mL in 1 mL | 12/8/2009 | |
| Antigen Laboratories, Inc. | 49288-9933 | INTRADERMAL, SUBCUTANEOUS | 0.004 mL in 1 mL | 12/8/2009 | |
| Deseret Biologicals, Inc. | 43742-1312 | ORAL | 12 [hp_X] in 1 mL | 5/27/2025 | |
| Dr. Donna Restivo DC | 62185-0062 | ORAL | 12 [hp_X] in 1 mL | 5/23/2025 | |
| Antigen Laboratories, Inc. | 49288-9934 | INTRADERMAL, SUBCUTANEOUS | 0.004 mL in 1 mL | 12/8/2009 | |
| CHAIN DRUG MARKETING ASSOCIATION | 83324-275 | ORAL | 1.4 g in 100 mL | 6/10/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| EGOPSORYL TA GEL | SIN05339P | OINTMENT | 0.500% w/w | 1/12/1991 | |
| HAEMOROL™, OILY PHENOL INJECTION 250MG/5ML | SIN02735P | INJECTION | 250mg / 5ml | 5/6/1989 | |
| CASTELLANI'S PAINT (STAINLESS) | SIN03372P | LIQUID | 4% w/w | 6/15/1989 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| CALOX CREAM | N/A | N/A | N/A | 2/22/1980 | |
| RADISOL ACID SALICYLIC APPLICATION | N/A | N/A | N/A | 1/24/1979 | |
| CURCYTOL SKIN LOTION (SPRAY) | N/A | N/A | N/A | 2/11/1998 | |
| PHENADERM SPRAY | N/A | N/A | N/A | 5/27/1988 | |
| ANTIVE SKIN LOTION | N/A | N/A | N/A | 9/19/1981 | |
| RELIEF SKIN LOTION | N/A | N/A | N/A | 3/31/1981 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| EGOPSORYL TA gel tube | 10616 | Medicine | A | 8/2/1991 | |
| THURSDAY PLANTATION TEA TREE COLD SORE cream tube | 50564 | Medicine | A | 2/9/1995 | |
| NYAL TOOTHACHE DROPS solution bottle | 13659 | Medicine | A | 9/10/1991 | |
| HEALAID CREAM tube | 28108 | Medicine | A | 11/13/1991 | |
| FONGYL ANTIFUNGAL PAINT bottle | 50084 | Lavit Kham | Medicine | A | 8/17/1994 |
| McGLOINS CHILBLAIN OINTMENT Tube | 11476 | McGloins Pty Ltd | Medicine | A | 8/13/1991 |
| GOLD CROSS CALAMINE SPRAY lotion bottle | 14291 | Medicine | A | 8/30/1991 | |
| HAEMOROL oily phenol 250mg/5mL Injection vial | 161711 | Medicine | A | 9/4/2009 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| PT POWDER PT LIQUID 1 PT LIQUID 2 | coralite dental products | 00070262 | Powder For Solution
,
Liquid - Dental | 9.5 % | 1/19/1993 |
| DERMAPHY ONT | produits phyto inc. | 00420212 | Ointment - Topical | .25 % | 12/31/1977 |
| OZONOL ONT | sterling winthrop inc. | 01905325 | Ointment - Topical | .18 % | 12/31/1992 |
| MEDICATED LIPBALM | norwood packaging ltd | 02286866 | Stick - Topical | 0.50 % | N/A |
| CARMEX LIP OINTMENT | carma laboratories inc | 02280779 | Ointment - Topical | 0.44 % | 1/5/2007 |
| CARMEX LIP BALM | carma laboratories inc | 02280760 | Ointment - Topical | 0.44 % | 1/5/2007 |
| STING-EZE-LIQ | wisconsin pharmacal co. llc | 02135965 | Liquid - Topical | 1.5 % | 12/31/1995 |
| DILUENT STERILE | omega laboratories limited | 00316288 | Liquid - Subcutaneous | 5 MG / ML | 12/31/1982 |
| WATKINS PETRO CARBO SALVE | watkins incorporated | 00365823 | Ointment - Topical | 495 MG / 28.3 G | 12/31/1949 |
| BOIL EASE DRAWING SALVE ONT | commerce pharmaceutics inc. | 00403504 | Ointment - Topical | .42 % | 12/31/1981 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| OTOCERUM GOTAS OTICAS EN SOLUCION | Laboratorio Reig Jofre, S.A. | 32103 | GOTAS ÓTICAS EN SOLUCIÓN | Sin Receta | Commercialized |
| OTOGEN CALMANTE | Laboratorios Ern S.A. | 46544 | GOTAS ÓTICAS EN SOLUCIÓN | Sin Receta | Commercialized |
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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