Clozapine
- Generic Name
- Clozapine
- Brand Names
- Clozaril, Fazaclo, Versacloz
- Drug Type
- Small Molecule
- Chemical Formula
- C18H19ClN4
- CAS Number
- 5786-21-0
- Unique Ingredient Identifier
- J60AR2IKIC
- Background
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical".. This low affinity to dopamine receptors results in fewer extrapyramida...
- Indication
Clozapine is indicated for the treatment of severely ill patients with schizophrenia who fail to respond adequately to standard antipsychotic treatment. Because of the risks of severe neutropenia and of seizure associated with its use, Clozapine should be used only in patients who have failed to respond adequately to standard antipsychotic treatment.
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- Associated Conditions
- Suicidal Behaviour, Treatment Resistant Schizophrenia, Advanced dopaminomimetic psychosis
- Associated Therapies
- -
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