MedPath

Bromhexine

Generic Name
Bromhexine
Drug Type
Small Molecule
Chemical Formula
C14H20Br2N2
CAS Number
3572-43-8
Unique Ingredient Identifier
Q1J152VB1P

Overview

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. Recently, bromhexine and its metabolite ambroxol have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

Background

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. Recently, bromhexine and its metabolite ambroxol have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.

Indication

Bromohexine is used alone or with other ingredients such as diphenhydramine, dextromethorphan, and guaifenesin to reduce mucus viscosity and clear mucus in conditions associated with mucus hypersecretion, including the common cold, influenza, respiratory tract infections, or other conditions.

Associated Conditions

  • Bronchiectasis
  • Common Cold
  • Cough
  • Cough caused by Common Cold
  • Nasal Congestion
  • Whooping Cough

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

VASICAN TABLET 8 mg
Manufacturer:PT. ACTAVIS INDONESIA
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1989/04/18
Approval:SIN02528P
BROMXINE TABLET 8 mg
Manufacturer:ATLANTIC LABORATORIES CORPN LTD
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1997/01/13
Approval:SIN09127P
VASICAN SYRUP 4 MG/5ML
Manufacturer:PT.ACTAVIS INDONESIA
Form:SYRUP
Strength:4 mg/5 ml
Online:Yes
Approved: 1989/05/22
Approval:SIN02864P
BROMHEXINE TABLET 8 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1989/03/06
Approval:SIN02479P
AXCEL BROMHEXINE TABLET 8 mg
Manufacturer:KOTRA PHARMA (M) SDN BHD
Form:TABLET
Strength:8 mg
Online:Yes
Approved: 1999/04/30
Approval:SIN10906P

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