Alvimopan
- Generic Name
- Alvimopan
- Brand Names
- Entereg
- Drug Type
- Small Molecule
- Chemical Formula
- C25H32N2O4
- CAS Number
- 156053-89-3
- Unique Ingredient Identifier
- Q153V49P3Z
- Background
Alvimopan is a peripherally acting μ opioid antagonist. It is used to avoid postoperative ileus following small or large bowel resection and accelerates the gastrointestinal recovery period.
- Indication
用于手术以及使用阿片类药物导致的胃肠功能紊乱，特发性便秘以及肠易激综合症等。
- Associated Conditions
- -
- Associated Therapies
- Gastrointestinal Recovery
A Study of Surgical Techniques During Cystectomy
- First Posted Date
- 2024-11-25
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 530
- Registration Number
- NCT06703476
- Locations
- 🇺🇸
Memorial Sloan Kettering at Basking Ridge (Consent Only), Basking Ridge, New Jersey, United States
🇺🇸Memorial Sloan Kettering Monmouth (Consent Only), Middletown, New Jersey, United States
🇺🇸Memorial Sloan Kettering Bergen (Consent Only), Montvale, New Jersey, United States
Alvimopan as a Rescue Treatment of Postoperative Ileus
- First Posted Date
- 2020-05-28
- Last Posted Date
- 2024-03-06
- Lead Sponsor
- Scott Steele
- Target Recruit Count
- 58
- Registration Number
- NCT04405037
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC
- First Posted Date
- 2017-11-24
- Last Posted Date
- 2021-08-18
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 84
- Registration Number
- NCT03352414
- Locations
- 🇺🇸
UCSD Moores Cancer Center, La Jolla, California, United States
Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
- First Posted Date
- 2017-07-13
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 136
- Registration Number
- NCT03216525
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Alvimopan Use in Polytraumatized Patients
- First Posted Date
- 2017-03-03
- Last Posted Date
- 2020-02-05
- Lead Sponsor
- University of Puerto Rico
- Target Recruit Count
- 3
- Registration Number
- NCT03068975
- Locations
- 🇵🇷
Puerto Rico Trauma Hospital, San Juan, Puerto Rico
Trial of Alvimopan in Major Spine Surgery
- First Posted Date
- 2016-06-02
- Last Posted Date
- 2020-12-01
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 49
- Registration Number
- NCT02789111
- Locations
- 🇺🇸
University of Virginia, Charlottesville, Virginia, United States
Ketamine in Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2016-05-27
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- Medical College of Wisconsin
- Registration Number
- NCT02785003
- Locations
- 🇺🇸
Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin, United States
Alvimopan as Rescue in Post op Ileus
- First Posted Date
- 2016-04-18
- Last Posted Date
- 2022-11-18
- Lead Sponsor
- Sharon Stein
- Target Recruit Count
- 14
- Registration Number
- NCT02742181
- Locations
- 🇺🇸
University Hospitals Case Medical Center, Cleveland, Ohio, United States
Gastrointestinal Tract Recovery in Patients Undergoing Open Ventral Hernia Repair
- First Posted Date
- 2015-03-05
- Last Posted Date
- 2019-11-14
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 10
- Registration Number
- NCT02379858
- Locations
- 🇺🇸
Froedtert & the Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Alvimopan and Ileus in PSF
- First Posted Date
- 2014-08-18
- Last Posted Date
- 2019-05-17
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 31
- Registration Number
- NCT02218190
- Locations
- 🇺🇸
Barnes Jewish Hospital / Washington University in St. Louis School of Medicine, Saint Louis, Missouri, United States
Drug Development Updates
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