MedPath

Eugenol

Generic Name
Eugenol
Drug Type
Small Molecule
Chemical Formula
C10H12O2
CAS Number
97-53-0
Unique Ingredient Identifier
3T8H1794QW

Overview

Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved products (including OTC), eugenol has been found to have anti-inflammatory, neuroprotective, antipyretic, antioxidant, antifungal and analgesic properties. Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction. There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache.

Background

Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved products (including OTC), eugenol has been found to have anti-inflammatory, neuroprotective, antipyretic, antioxidant, antifungal and analgesic properties. Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction. There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache.

Indication

Eugenol is not currently available in any FDA-approved drug products. There are a number of unapproved OTC products that advertise it for the use of toothache. Eugenol is is also commonly used in combination with zinc oxide in dental procedures for the cementation of temporary prostheses and the temporary restoration of teeth and cavities.

Associated Conditions

  • Contusions
  • Insect Bites
  • Myalgia
  • Pruritis of the skin
  • Sprains
  • Oral discomfort and pain

FDA Approved Products

Dry Socket
Manufacturer:Dentsply LLC, Professional Division, trading as "Sultan Healthcare"
Route:DENTAL
Strength:0.0416 g in 1 g
Approved: 2024/01/26
NDC:0699-0404

Singapore Approved Products

No Singapore products found for this drug

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