Eugenol
- Generic Name
- Eugenol
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C10H12O2
- CAS Number
- 97-53-0
- Unique Ingredient Identifier
- 3T8H1794QW
- Background
Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. Although not currently available in any FDA-approved products (including OTC), eugenol has been found to have anti-inflammatory, neuroprotective, antipyretic, antioxidant, antifungal and analgesic properties. Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction.
There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache.
- Indication
Eugenol is not currently available in any FDA-approved drug products. There are a number of unapproved OTC products that advertise it for the use of toothache. Eugenol is is also commonly used in combination with zinc oxide in dental procedures for the cementation of temporary prostheses and the temporary restoration of teeth and cavities.
- Associated Conditions
- Contusions, Insect Bites, Myalgia, Pruritis of the skin, Sprains, Oral discomfort and pain
- Associated Therapies
- -
Herbal extracts in orofacial pain: a systematic review and direct and indirect meta-analysis
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