Oxytocin
- Generic Name
- Oxytocin
- Brand Names
- Pitocin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 50-56-6
- Unique Ingredient Identifier
- 1JQS135EYN
- Background
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...
- Indication
Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...
- Associated Conditions
- Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
- Associated Therapies
- Reinforcement of labor
PK Sampling After IV Oxytocin and Effects on Sensory Function in Healthy Volunteers
- First Posted Date
- 2019-04-26
- Last Posted Date
- 2021-05-13
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 11
- Registration Number
- NCT03929367
- Locations
- 🇺🇸
Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States
A Pharmaco-imaging Approach to Predicting Social Functioning and Clinical Responses to Oxytocin Administration in Schizophrenia
- First Posted Date
- 2019-04-03
- Last Posted Date
- 2024-04-24
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 26
- Registration Number
- NCT03900754
- Locations
- 🇺🇸
VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles, California, United States
🇺🇸San Francisco VA Medical Center, San Francisco, CA, San Francisco, California, United States
Carbetocin Myocardium Trial 2014 Part 2
- First Posted Date
- 2019-04-02
- Last Posted Date
- 2022-05-26
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT03899961
- Locations
- 🇳🇴
Akershus University Hospital, Lørenskog, Norway
🇳🇴Division of Anaesthesia and Intensive Care Medicine, Oslo University Hospital - Rikshospitalet, Oslo, Norway
Pharmacokinetics of Oxytocin at Cesarean Delivery
- First Posted Date
- 2019-04-02
- Last Posted Date
- 2020-05-07
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 30
- Registration Number
- NCT03898882
- Locations
- 🇺🇸
Washington University in St. Louis, Saint Louis, Missouri, United States
The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean Section
- Conditions
- Interventions
- First Posted Date
- 2019-04-02
- Last Posted Date
- 2022-11-02
- Target Recruit Count
- 200
- Registration Number
- NCT03899597
- Locations
- 🇨🇿
Institute for the Care of Mother and Child, Prague, Czechia
Intravenous Oxytocin Versus Tranexamic Acid in Reducing Blood Loss During Abdominal Myomectomy.
- First Posted Date
- 2019-03-27
- Last Posted Date
- 2020-04-28
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT03892668
- Locations
- 🇪🇬
faculty of medicine Cairo university, Giza, Egypt
Oxytocin and Dopamine's Effect on Vicarious Optimism
- Conditions
- Interventions
- First Posted Date
- 2019-03-26
- Last Posted Date
- 2019-03-26
- Lead Sponsor
- Beijing Normal University
- Target Recruit Count
- 156
- Registration Number
- NCT03891095
- Locations
- 🇨🇳
Beijing Normal University, Beijing, Beijing, China
The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories
- First Posted Date
- 2019-03-14
- Last Posted Date
- 2023-04-04
- Lead Sponsor
- Charite University, Berlin, Germany
- Target Recruit Count
- 217
- Registration Number
- NCT03875391
- Locations
- 🇩🇪
Charité- Universitätsmedizin Berlin, Berlin, Germany
Carbetocin Versus Oxytocin Plus Sublingual Misoprostol in the Management of Atonic Postpartum Hemorrhage
- Conditions
- Interventions
- First Posted Date
- 2019-03-12
- Last Posted Date
- 2021-09-29
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 135
- Registration Number
- NCT03870503
- Locations
- 🇪🇬
Aswan University Hospital, Aswan, Egypt
Oxytocin on Approach Bias and Craving
- First Posted Date
- 2019-03-07
- Last Posted Date
- 2022-06-06
- Lead Sponsor
- Jennifer Mitchell
- Registration Number
- NCT03865615
- Locations
- 🇺🇸
University of California, San Francisco, Berkeley, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.