Oxytocin
- Generic Name
- Oxytocin
- Brand Names
- Pitocin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 50-56-6
- Unique Ingredient Identifier
- 1JQS135EYN
- Background
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recog...
- Indication
Administration of exogenous oxytocin is indicated in the antepartum period to initiate or improve uterine contractions for vaginal delivery in situations where there is fetal or maternal concern. For example, It may be used to induce labor in cases of Rh sensitization, maternal diabetes, preeclampsia at or near term, and when delivery is indicated due to pre...
- Associated Conditions
- Incomplete Abortion, Inevitable abortion, Postpartum Bleeding
- Associated Therapies
- Reinforcement of labor
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
- Conditions
- Interventions
- First Posted Date
- 2019-03-01
- Last Posted Date
- 2023-01-09
- Lead Sponsor
- Vivek Jain
- Target Recruit Count
- 40
- Registration Number
- NCT03860233
- Locations
- 🇺🇸
Medical Faculty Associates, Washington, District of Columbia, United States
Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium
- Conditions
- Interventions
- First Posted Date
- 2019-02-25
- Last Posted Date
- 2022-10-25
- Target Recruit Count
- 33
- Registration Number
- NCT03852797
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)
- First Posted Date
- 2019-02-19
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 194
- Registration Number
- NCT03846505
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
Effects of Oxytocin and Lorazepam on Fear-related Intra-amygdalar Activity
- Conditions
- Interventions
- First Posted Date
- 2019-02-04
- Last Posted Date
- 2019-04-17
- Lead Sponsor
- University Hospital, Bonn
- Target Recruit Count
- 120
- Registration Number
- NCT03829839
- Locations
- 🇩🇪
Department of Psychiatry, University of Bonn, Bonn, Germany
Mindfulness Training Plus Oxytocin Effects on Smoking Behavior
- Conditions
- Interventions
- First Posted Date
- 2019-01-28
- Last Posted Date
- 2024-06-14
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 20
- Registration Number
- NCT03819231
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2018-12-17
- Last Posted Date
- 2019-02-15
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 400
- Registration Number
- NCT03777878
- Locations
- 🇪🇬
Aswan University, Aswan, Egypt
Carbetocin Versus Oxytocin for the Prevention of Postpartum Hemorrhage in Emergency Caesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2018-11-28
- Last Posted Date
- 2018-11-28
- Lead Sponsor
- Al-Kindy College of Medicine
- Target Recruit Count
- 300
- Registration Number
- NCT03755531
- Locations
- 🇮🇶
Al Kindy College of Medicine/ University of Baghdad, Baghdad, Iraq
A Randomized Trial of Oral Misoprostol Alone Versus Oral Misoprostol Followed by Oxytocin for Labour Induction
- First Posted Date
- 2018-11-21
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- University of Liverpool
- Target Recruit Count
- 520
- Registration Number
- NCT03749902
- Locations
- 🇮🇳
Daga Memorial Women's Hospital, Nagpur, Maharashtra, India
🇮🇳Government Medical College (GMC), Nagpur, India
🇮🇳Mahatma Gandhi Institute of Medical Sciences, Sevagram, Maharashtra, India
Does Induction Dosage in Latent Phase Affect Active Phase of Labor?
- First Posted Date
- 2018-11-15
- Last Posted Date
- 2021-01-20
- Target Recruit Count
- 300
- Registration Number
- NCT03742531
- Locations
- 🇹🇷
Zeynep Kamil Education and Research Hospital, Istanbul, Turkey
Tranexamic Acid Plus Buccal Misoprostol on Blood Loss During and After Cesarean Delivery
- Conditions
- Interventions
- First Posted Date
- 2018-10-18
- Last Posted Date
- 2020-07-14
- Lead Sponsor
- Aswan University Hospital
- Target Recruit Count
- 400
- Registration Number
- NCT03710304
- Locations
- 🇪🇬
Aswan University, Aswan, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.