Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation
Clinical Trials
Related News

Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia

Not Applicable
Conditions
Anesthesia
Pain
Interventions
Drug: Normal saline
Drug: Remifentanil
First Posted Date
2016-03-09
Last Posted Date
2021-01-07
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
54
Registration Number
NCT02703090
Locations
🇺🇸

Boston Children's Hospital, Boston, Massachusetts, United States

Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia

First Posted Date
2016-02-17
Last Posted Date
2024-04-18
Lead Sponsor
University Hospital, Geneva
Registration Number
NCT02683837
Locations
🇨🇭

Geneva Children's Hospital, Geneva, Switzerland

Anesthetic Techniques in EP Patients

First Posted Date
2016-01-27
Last Posted Date
2020-09-22
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
35
Registration Number
NCT02664922
Locations
🇺🇸

Ronald Reagan UCLA Medical Center, Los Angeles, California, United States

Remifentanil Requirement for Acceptable Intubating Condition

First Posted Date
2016-01-14
Last Posted Date
2019-01-10
Lead Sponsor
Ajou University School of Medicine
Target Recruit Count
51
Registration Number
NCT02655380
Locations
🇰🇷

Ajou universitiy school of medicine, Suwon-si, Gyeong-gi Do, Korea, Republic of

Bispectral Index Under Propofol Anesthesia in Children : a Study Between TIVA and TCI

Not Applicable
Completed
Conditions
Anesthesia
Interventions
Device: EEG Monitoring
Drug: Remifentanil
First Posted Date
2015-12-22
Last Posted Date
2015-12-22
Lead Sponsor
Pr Isabelle CONSTANT
Target Recruit Count
66
Registration Number
NCT02637726
Locations
🇫🇷

Departement d'anesthesie Hopital Armand Trousseau, Paris, France

the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation

First Posted Date
2015-12-21
Last Posted Date
2015-12-21
Lead Sponsor
The First Affiliated Hospital of Zhengzhou University
Target Recruit Count
1500
Registration Number
NCT02635802

Cognitive Functions After TIVA With Dexmedetomidine

First Posted Date
2015-12-16
Last Posted Date
2024-05-17
Lead Sponsor
Uludag University
Target Recruit Count
40
Registration Number
NCT02631135
Locations
🇹🇷

Uludag University, Bursa, Turkey

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Procedure: Elective surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Isoflurane
Drug: Desflurane
Drug: Scopolamine
Drug: Droperidol
Drug: Haloperidol
Drug: Dexamethasone
Drug: Promethazine
Drug: Meclizine
Drug: Aprepitant
Drug: Metoclopramide
Drug: Fentanyl
Drug: Sufentanil
Drug: Alfentanil
Drug: Remifentanil
Drug: Morphine
Drug: Meperidine
Drug: Hydromorphone
Drug: Methadone
Drug: Oxycodone
Drug: Oxymorphone
Drug: Hydrocodone
Drug: Ketamine
Drug: Ondansetron
Drug: Granisetron
Drug: Dolasetron mesylate
Drug: Palonosetron
Drug: Tropisetron
Drug: Ramosetron
First Posted Date
2015-12-09
Last Posted Date
2019-03-07
Lead Sponsor
Vanderbilt University
Target Recruit Count
27034
Registration Number
NCT02625181
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Remifentanil and Fentanyl in Dental Surgery (REFEDS)

Not Applicable
Completed
Conditions
Postoperative Pain
Interventions
Drug: Remifentanil
Drug: Fentanyl
First Posted Date
2015-12-02
Last Posted Date
2015-12-02
Lead Sponsor
Attikon Hospital
Target Recruit Count
46
Registration Number
NCT02619032
Locations
🇬🇷

2nd Department of Anesthesiology, Attikon University Hospital, Athens, Attiki, Greece

Experimental Medicine Study to Validate Pharmacodynamic Pain Assessments in Healthy Volunteers With an Opioid Analgesic (Remifentanil)

Phase 1
Completed
Conditions
Pain
Interventions
Drug: Placebo
Drug: Remifentanil
First Posted Date
2015-11-11
Last Posted Date
2015-11-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
20
Registration Number
NCT02602002
Locations
🇰🇷

GSK Investigational Site, Seoul, Korea, Republic of

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