Galantamine
- Generic Name
- Galantamine
- Brand Names
- Razadyne
- Drug Type
- Small Molecule
- Chemical Formula
- C17H21NO3
- CAS Number
- 357-70-0
- Unique Ingredient Identifier
- 0D3Q044KCA
- Background
Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantam...
- Indication
Galantamine is indicated for the treatment of mild to moderate dementia of the Alzheimer’s type.
- Associated Conditions
- Mild to Moderate Dementia Due to Alzheimer's Disease, Mild Dementia of the Alzheimer's Type, Moderate Alzheimer's Type Dementia
- Associated Therapies
- -
A Placebo-controlled Trial to Evaluate the Safety and Efficacy of Galantamine in the Treatment of Vascular Dementia
- Conditions
- First Posted Date
- 2002-05-03
- Last Posted Date
- 2011-06-08
- Target Recruit Count
- 254
- Registration Number
- NCT00035191
A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease
- Conditions
- First Posted Date
- 2002-05-03
- Last Posted Date
- 2011-06-08
- Target Recruit Count
- 63
- Registration Number
- NCT00035204
Evaluation of Galantamine in the Treatment of Alzheimer's Disease
- Conditions
- First Posted Date
- 1999-11-01
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Janssen, LP
- Registration Number
- NCT00000172
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸VAPS Health Care System, Seattle, Washington, United States
🇺🇸Indiana Alzheimer's University Clinic, Indianapolis, Indiana, United States
Drug Development Updates
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