Dalteparin

Generic Name
Dalteparin
Brand Names
Fragmin
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
9005-49-6
Unique Ingredient Identifier
S79O08V79F
Background

Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000. LMWHs have a more pre...

Indication

Dalteparin is used as a prophylaxis for deep-vein thrombosis and pulmonary embolisms in patients undergoing general surgery (e.g., abdominal, gynecologic, urologic), and in patients with acute medical conditions (e.g. cancer, bed rest, heart failure, severe lung disease). It is also used in patients who have severely restricted mobility, which poses a risk f...

Associated Conditions
Cardiovascular Events, Clotting, Deep Vein Thrombosis, Symptomatic Venous Thromboembolism, Venous Thromboembolism
Associated Therapies
-

Dalteparin and Sunitinib Malate as First-Line Therapy in Treating Patients With Kidney Cancer That is Metastatic or Cannot Be Removed by Surgery

First Posted Date
2010-02-03
Last Posted Date
2022-08-05
Lead Sponsor
Roswell Park Cancer Institute
Target Recruit Count
16
Registration Number
NCT01061411
Locations
🇳🇱

Academ Zienkenhuis Bij De University, Amsterdam, Netherlands

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

and more 1 locations

The Clinical Utility of Thrombelastography in Guiding Prophylaxis of Venous Thromboembolism Following Trauma

First Posted Date
2010-01-15
Last Posted Date
2019-01-08
Lead Sponsor
Denver Health and Hospital Authority
Target Recruit Count
50
Registration Number
NCT01050153
Locations
🇺🇸

Denver Health Medical Center, Denver, Colorado, United States

TIPPS: Thrombophilia in Pregnancy Prophylaxis Study

First Posted Date
2009-08-27
Last Posted Date
2014-05-19
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
292
Registration Number
NCT00967382
Locations
🇨🇦

SMBD Jewish General Hospital, Montreal, Quebec, Canada

🇨🇦

Royal University Hospital, Saskatoon, Saskatchewan, Canada

🇨🇦

QEII Health Sciences Centre, Halifax, Nova Scotia, Canada

and more 9 locations

Dalteparin for Primary Venous Thromboembolism (VTE) Prophylaxis in Pancreatic Cancer Patients

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-08-26
Last Posted Date
2016-12-12
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
87
Registration Number
NCT00966277
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Fragmin for the Treatment of Acute VTE in Pediatric Cancer Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2009-08-06
Last Posted Date
2019-04-16
Lead Sponsor
Pfizer
Target Recruit Count
38
Registration Number
NCT00952380
Locations
🇸🇮

Lekarna, Univerzitetni klinicni center Ljubljana, Ljubljana, Slovenia

🇺🇸

Children's Hospital Colorado, Aurora, Colorado, United States

🇺🇸

Investigational Drug Service Tampa General Hospital, Tampa, Florida, United States

and more 23 locations

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-07-21
Last Posted Date
2024-04-18
Lead Sponsor
Pfizer
Target Recruit Count
338
Registration Number
NCT00942968
Locations
🇨🇦

University Health Network-Toronto General Hospital, Toronto, Ontario, Canada

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

Bay Area Cancer Research Group, Pleasant Hill, California, United States

and more 39 locations

Effectiveness And Safety Of Dalteparin In Patients With Acute Coronary Syndromes Without ST Elevations In Clinical Practice

Completed
Conditions
Interventions
First Posted Date
2009-06-17
Last Posted Date
2012-01-23
Lead Sponsor
Pfizer
Target Recruit Count
618
Registration Number
NCT00922766
Locations
🇮🇳

Pfizer Investigational Site, Kolkata, West Bengal, India

Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)

First Posted Date
2008-11-06
Last Posted Date
2016-03-07
Lead Sponsor
Duke University
Target Recruit Count
1884
Registration Number
NCT00786474
Locations
🇺🇸

Duke Clinical Research Institute, Durham, North Carolina, United States

The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (A6301086)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-10-02
Last Posted Date
2012-01-13
Lead Sponsor
Pfizer
Target Recruit Count
62
Registration Number
NCT00765063
Locations
🇬🇧

Pfizer Investigational Site, Birmingham, United Kingdom

Alterations of Blood Clotting With the Use of Sequential Compression Devices on the Lower Limbs

First Posted Date
2008-08-01
Last Posted Date
2013-11-05
Lead Sponsor
University of Parma
Target Recruit Count
40
Registration Number
NCT00726570
Locations
🇮🇹

University Hospital / Azienda Ospedaliero-Universitaria, Parma, PR, Italy

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