MedPath

Ropidoxuridine

Generic Name
Ropidoxuridine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C9H11IN2O4
CAS Number
93265-81-7
Unique Ingredient Identifier
3HX21A3SQF
Background

Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.

Indication

Investigated for use/treatment in cancer/tumors (unspecified).

Associated Conditions
-
Associated Therapies
-
biospace.com
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Shuttle Pharma Doses First Patients in Phase 2 Clinical Trial of Ropidoxuridine for ...

Shuttle Pharmaceuticals initiated Phase 2 trial of Ropidoxuridine for glioblastoma, aiming to improve RT outcomes. The trial will determine optimal dosing and evaluate survival rates against historical controls, expected to complete in 18-24 months.
biospace.com
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Shuttle Pharma Completes Clinical Trial Site Enrollment for Phase 2 of Ropidoxuridine

Shuttle Pharmaceuticals has finalized agreements with six cancer centers for its Phase 2 clinical trial of Ropidoxuridine, a radiation sensitizer for glioblastoma treatment. Patients are currently being screened for enrollment, with the trial expected to complete within 18 to 24 months.
globenewswire.com
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Shuttle Pharma Completes Clinical Trial Site Enrollment for

Shuttle Pharmaceuticals has finalized agreements with six cancer centers for its Phase 2 clinical trial of Ropidoxuridine, a radiation sensitizer for glioblastoma treatment. The trial aims to determine an optimal dose and expects to complete within 18-24 months, with potential to improve cancer cure rates and patient survival.
stocktitan.net
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Shuttle Pharma Expands Clinical Trial Site Enrollment for Phase 2 of Ropidoxuridine

Shuttle Pharmaceuticals expands Phase 2 trial for Ropidoxuridine, a radiation sensitizer for glioblastoma, adding two sites to total four out of six planned. Targeting IDH wild-type, methylation negative patients, the trial aims to improve outcomes for this aggressive brain cancer. The study will enroll 40 patients initially, with an additional 14 to achieve statistical significance, expected to complete in 18-24 months.
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