IDE161

Manufacturers: IDEAYA Biosciences, Inc.

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Mechanism of Action

PARG inhibitor. IDE161 prevents the removal of poly(ADP-ribose) chains generated by PARP during the DNA damage response, leading to persistent PARylation and impaired resolution of DNA repair complexes.

Drugs

Data Sources:ClinicalTrials.govEU CTRFDAEMANMPATGAHealth CanadaWHO ICTRP

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IDE161

Manufacturers: IDEAYA Biosciences, Inc.

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Mechanism of Action

Drugs