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Cinnarizine

Generic Name
Cinnarizine
Drug Type
Small Molecule
Chemical Formula
C26H28N2
CAS Number
298-57-7
Unique Ingredient Identifier
3DI2E1X18L

Overview

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. Combination use of cinnarizine with other nootropics, such as piracetam resulted in enhanced effect of boosting brain oxygen supply.

Background

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. Combination use of cinnarizine with other nootropics, such as piracetam resulted in enhanced effect of boosting brain oxygen supply.

Indication

For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.

Associated Conditions

  • Balance Disorders
  • Dizziness
  • Motion Sickness
  • Nausea
  • Peripheral Arterial Disease (PAD)
  • Raynaud's Phenomenon
  • Vertigo
  • Inadequate cerebral circulation
  • Peripheral vasculopathy

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

CINNARON 25 TABLET 25 mg
Manufacturer:REMEDICA LTD
Form:TABLET
Strength:25 mg
Online:Yes
Approved: 1989/05/22
Approval:SIN02924P
AXCEL CINNARIZINE TABLETS 25 mg
Manufacturer:KOTRA PHARMA (M) SDN BHD
Form:TABLET
Strength:25 mg
Online:Yes
Approved: 1999/05/17
Approval:SIN10935P
CINNA TABLET 25 mg
Manufacturer:Y S P INDUSTRIES (M) SDN BHD
Form:TABLET
Strength:25 mg
Online:Yes
Approved: 1995/12/16
Approval:SIN08482P
STUGERON TABLET 25 mg
Manufacturer:JANSSEN CILAG S P A
Form:TABLET
Strength:25 mg
Online:Yes
Approved: 1988/05/13
Approval:SIN01122P
CELENID TABLET 25 mg
Manufacturer:BIOLAB CO LTD
Form:TABLET
Strength:25 mg
Online:Yes
Approved: 1991/08/21
Approval:SIN06513P

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