Sodium lauryl sulfate

Generic Name
Sodium lauryl sulfate
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C12H25NaO4S
CAS Number
151-21-3
Unique Ingredient Identifier
368GB5141J
Background

Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.

Indication

SLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.

Associated Conditions
-
Associated Therapies
-

Dermal Tolerability of Dapsone Gel in Healthy Volunteers

First Posted Date
2014-04-21
Last Posted Date
2018-10-09
Lead Sponsor
Almirall, S.A.
Target Recruit Count
237
Registration Number
NCT02117752

Dermal Safety Study to Evaluate Potential Irritation of Abametapir Lotion

First Posted Date
2014-02-13
Last Posted Date
2021-07-26
Lead Sponsor
Dr. Reddy's Laboratories Limited
Target Recruit Count
40
Registration Number
NCT02061813
Locations
🇺🇸

TKL Reserach Inc, Paramus, New Jersey, United States

21 Day Irritancy Test of Azelaic Acid Pre-foam Formulation

First Posted Date
2011-09-08
Last Posted Date
2020-04-01
Lead Sponsor
LEO Pharma
Target Recruit Count
40
Registration Number
NCT01430312
Locations
🇺🇸

Robert I. Cooper, MD, Fargo, North Dakota, United States

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