Insulin Lispro

Generic Name
Insulin Lispro
Brand Names
Admelog, Humalog, Humalog Mix, Humalog kwikpen, Liprolog, Lyumjev, Insulin lispro Sanofi, Lyumjev (previously Liumjev)
Drug Type
Biotech
Chemical Formula
-
CAS Number
133107-64-9
Unique Ingredient Identifier
GFX7QIS1II
Background

Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas that promotes glucose metabolism. Insulin is release...

Indication

本品尤其适用于下列情况:

1.经常发生低血糖的1型糖尿病者,使用本品可减少低血糖的发生率;

2.生活不规律,外出活动较多的用胰岛素治疗的糖尿病患者,本品快速、短效的特点有助于及时调整胰岛素的用量。

Associated Conditions
Diabetes Mellitus, Diabetic Ketoacidosis, Gestational Diabetes Mellitus (GDM)
Associated Therapies
-

Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes

First Posted Date
2015-08-18
Last Posted Date
2015-08-20
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
70
Registration Number
NCT02526810
Locations
🇨🇳

Endocrinology department of the Third Affiliated Hospital of Sun Yet-san University, Guangzhou City, Guangdong, China

Single Dose Clamp Study to Evaluate Concentration-time Profile and Metabolic Activity of 3 Dose Levels of Afrezza and 3 Dose Levels of Insulin Lispro in Patients With Type 1 Diabetes Mellitus

First Posted Date
2015-06-12
Last Posted Date
2017-04-13
Lead Sponsor
Mannkind Corporation
Target Recruit Count
30
Registration Number
NCT02470637
Locations
🇩🇪

Investigational Site Number 276001, Neuss, Germany

Normal Versus Dual Wave Insulin Bolus for High-protein Food

First Posted Date
2014-10-28
Last Posted Date
2018-01-31
Lead Sponsor
Medical University of Warsaw
Target Recruit Count
70
Registration Number
NCT02276859
Locations
🇵🇱

Department of Pediatrics, Medical University of Warsaw, Poland, Warsaw, Poland

A Study to Compare Pharmacokinetics and Pharmacodynamics of SAR342434 to Insulin Lispro in Subjects With Type 1 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-10-23
Last Posted Date
2014-10-23
Lead Sponsor
Sanofi
Target Recruit Count
30
Registration Number
NCT02273258
Locations
🇩🇪

Sanofi Administrative Office, Frankfurt, Germany

A Trial to Compare the PK and PD of Insulin Lispro Administered Into Different Tissues in Subjects With Diabetes Mellitus Type 1

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-08-20
Last Posted Date
2014-12-30
Lead Sponsor
Profil Institut für Stoffwechselforschung GmbH
Target Recruit Count
18
Registration Number
NCT02221323
Locations
🇩🇪

Profil Institut für Stoffwechselforschung GmbH, Neuss, NRW, Germany

A Study To Compare the Effects of Insulin Peglispro and Glargine on Insulin Sensitivity and Meal Time Insulin Requirements in Type 2 Diabetics

First Posted Date
2014-07-22
Last Posted Date
2018-11-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
24
Registration Number
NCT02197520
Locations
🇺🇸

Profil Institute for Clinical Research Inc, Chula Vista, California, United States

A Study to Compare and Measure the Effects of Insulin Peglispro (LY2605541) and Glargine on Meal Time Insulin Requirements

First Posted Date
2014-06-02
Last Posted Date
2019-03-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
28
Registration Number
NCT02152384
Locations
🇩🇪

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Neuss, Germany

A Study of LY2605541 and Insulin Lispro Mixture in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-06-06
Last Posted Date
2014-10-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
40
Registration Number
NCT01871493
Locations
🇸🇬

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Singapore, Singapore

CONSISTENT 1: Metabolic and Safety Outcomes of Hylenex Recombinant (Hyaluronidase Human Injection) Preadministered at CSII Infusion Site in Participants With Type 1 Diabetes Mellitus (T1DM)

First Posted Date
2013-05-08
Last Posted Date
2018-11-07
Lead Sponsor
Halozyme Therapeutics
Target Recruit Count
456
Registration Number
NCT01848990
Locations
🇺🇸

For additional information regarding investigative sites for this trial, call (858) 794-8889 8 AM to 5 PM Mon-Fri Pacific Standard Time, Madison, Wisconsin, United States

Pharmacokinetic and Injection Site Toleration of BIOD-238 and BIOD-250 Compared to Humalog® in Subjects With Type 1 Diabetes

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-03-15
Last Posted Date
2013-03-15
Lead Sponsor
Biodel
Target Recruit Count
12
Registration Number
NCT01811849
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