Doxazosin
- Generic Name
- Doxazosin
- Brand Names
- Cardura
- Drug Type
- Small Molecule
- Chemical Formula
- C23H25N5O5
- CAS Number
- 74191-85-8
- Unique Ingredient Identifier
- NW1291F1W8
- Background
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved by the FDA in 199...
- Indication
Doxazosin is indicated to treat the symptoms of benign prostatic hypertrophy, which may include urinary frequency, urgency, and nocturia, among other symptoms. In addition, doxazosin is indicated alone or in combination with various antihypertensive agents for the management of hypertension. Off-label uses of doxazosin include the treatment of pediatric hype...
- Associated Conditions
- Benign Prostatic Hyperplasia (BPH), Hypertension, Ureteric calculus
- Associated Therapies
- -
DOXAZOSIN FOR PTSD
- First Posted Date
- 2014-12-04
- Last Posted Date
- 2022-04-26
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 30
- Registration Number
- NCT02308202
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male Volunteers
- Conditions
- Interventions
- First Posted Date
- 2014-10-17
- Last Posted Date
- 2014-10-17
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 97
- Registration Number
- NCT02266537
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
- First Posted Date
- 2013-10-01
- Last Posted Date
- 2020-02-20
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 43
- Registration Number
- NCT01953432
- Locations
- 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas, United States
Doxazosin an a1 Antagonist for Alcohol Dependence
- First Posted Date
- 2011-09-20
- Last Posted Date
- 2015-07-22
- Lead Sponsor
- Brown University
- Target Recruit Count
- 48
- Registration Number
- NCT01437046
- Locations
- 🇺🇸
Brown University Center for Alcohol and Addiction Studies, Providence, Rhode Island, United States
Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)
- Conditions
- Interventions
- First Posted Date
- 2011-06-30
- Last Posted Date
- 2018-12-11
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 16
- Registration Number
- NCT01386177
- Locations
- 🇨🇭
University Hospital Basel, Basel, Switzerland
Phenoxybenzamine Versus Doxazosin in PCC Patients
- First Posted Date
- 2011-06-23
- Last Posted Date
- 2018-01-31
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 134
- Registration Number
- NCT01379898
- Locations
- 🇳🇱
Department of Endocrinology, University Medical Center Groningen, Groningen, Netherlands
Pharmacogenetics of Doxazosin for Cocaine Dependence
- First Posted Date
- 2010-06-16
- Last Posted Date
- 2019-07-22
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 96
- Registration Number
- NCT01145183
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine
- Conditions
- Interventions
- First Posted Date
- 2010-02-04
- Last Posted Date
- 2012-07-27
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 13
- Registration Number
- NCT01062945
- Locations
- 🇺🇸
Michael Debakey VA Medical Center, Houston, Texas, United States
The Efficacy of Doxazosin for Cocaine Users
- First Posted Date
- 2009-04-14
- Last Posted Date
- 2019-08-22
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 35
- Registration Number
- NCT00880997
- Locations
- 🇺🇸
Baylor College of Medicine - Michael E. DeBakey VA Medical Center, Houston, Texas, United States
Effects of Chronic Use of Doxazosin in Men With Benign Prostatic Hyperplasia
- First Posted Date
- 2008-08-08
- Last Posted Date
- 2010-08-26
- Lead Sponsor
- Samsung Medical Center
- Target Recruit Count
- 25
- Registration Number
- NCT00730418
- Locations
- 🇰🇷
Samsung Medical Center, SEoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.