Diflunisal
- Generic Name
- Diflunisal
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H8F2O3
- CAS Number
- 22494-42-4
- Unique Ingredient Identifier
- 7C546U4DEN
- Background
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of pros...
- Indication
For symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.
- Associated Conditions
- Mild pain, Osteoarthritis (OA), Rheumatoid Arthritis, Moderate Pain
- Associated Therapies
- -
The Effects Diflunisal on the Levels of BMS-986165 in Healthy Participants
- First Posted Date
- 2019-10-03
- Last Posted Date
- 2020-08-05
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 48
- Registration Number
- NCT04113668
- Locations
- 🇺🇸
PRA Health Sciences - Lenexa, Lenexa, Kansas, United States
Pilot Study of Diflunisal in HIV-infected Adults
- First Posted Date
- 2012-08-30
- Last Posted Date
- 2017-10-27
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 8
- Registration Number
- NCT01676363
- Locations
- 🇨🇦
Immunodeficiency Clinic, St. Paul's Hospital, Vancouver, British Columbia, Canada
The Effect of Diflunisal on Familial Transthyretin Amyloidosis
- Conditions
- First Posted Date
- 2011-09-13
- Last Posted Date
- 2015-08-24
- Lead Sponsor
- Umeå University
- Target Recruit Count
- 55
- Registration Number
- NCT01432587
- Locations
- 🇸🇪
Dept of Clinical Medicin, Ptieå Hospital, Piteå, Sweden
🇸🇪Dept of Clinical Medicine, Umeå University Hospital, Umeå, Sweden
🇸🇪Dept of clinical medicin, Skellefteå Hospital, Skellefteå, Sweden
The Effect of Diflunisal on Familial Amyloidosis
- Conditions
- Interventions
- First Posted Date
- 2006-02-22
- Last Posted Date
- 2017-03-17
- Lead Sponsor
- Boston University
- Target Recruit Count
- 130
- Registration Number
- NCT00294671
- Locations
- 🇯🇵
Kumamoto University, Kumamoto, Japan
🇺🇸Mount Sinai School of Medicine, Department of Medicine, New York, New York, United States
🇮🇹IRCCS Policlinico San Matteo, Pavia, Italy
Drug Development Updates
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