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Diflunisal

Generic Name
Diflunisal
Drug Type
Small Molecule
Chemical Formula
C13H8F2O3
CAS Number
22494-42-4
Unique Ingredient Identifier
7C546U4DEN

Overview

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway. Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of rheumatoid arthritis and osteoarthritis.

Background

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid pathway. Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of rheumatoid arthritis and osteoarthritis.

Indication

For symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.

Associated Conditions

  • Mild pain
  • Osteoarthritis (OA)
  • Rheumatoid Arthritis
  • Moderate Pain

FDA Approved Products

Diflunisal
Manufacturer:Zydus Lifesciences Limited
Route:ORAL
Strength:500 mg in 1 1
Approved: 2022/11/16
NDC:70771-1083
DIFLUNISAL
Manufacturer:H. J. Harkins Company Inc.
Route:ORAL
Strength:500 mg in 1 1
Approved: 2017/12/21
NDC:52959-379
Diflunisal
Manufacturer:Chartwell RX, LLC
Route:ORAL
Strength:500 mg in 1 1
Approved: 2023/02/01
NDC:62135-456
Diflunisal
Manufacturer:Teva Pharmaceuticals USA, Inc.
Route:ORAL
Strength:500 mg in 1 1
Approved: 2021/10/29
NDC:0093-9222

Singapore Approved Products

No Singapore products found for this drug

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