MedPath

Ataciguat

Generic Name
Ataciguat
Drug Type
Small Molecule
Chemical Formula
C21H19Cl2N3O6S3
CAS Number
254877-67-3
Unique Ingredient Identifier
QP166M390Q
Background

Ataciguat has been investigated for the basic science of Aortic Valve Stenosis.

Ataciguat Shows Promise in Slowing Aortic Valve Stenosis Progression, Mayo Clinic Study Reveals

• A groundbreaking study at Mayo Clinic demonstrates that ataciguat reduced aortic valve calcification progression by 69.8% over six months compared to placebo in patients with moderate aortic valve stenosis. • The novel drug shows potential to delay or prevent valve replacement surgery, particularly benefiting younger patients who might otherwise need multiple surgeries throughout their lifetime. • Clinical trials confirm ataciguat's safety profile with minimal side effects, maintaining bone health while effectively slowing valve calcification, paving the way for upcoming Phase 3 trials.
© Copyright 2025. All Rights Reserved by MedPath