• A groundbreaking study at Mayo Clinic demonstrates that ataciguat reduced aortic valve calcification progression by 69.8% over six months compared to placebo in patients with moderate aortic valve stenosis.
• The novel drug shows potential to delay or prevent valve replacement surgery, particularly benefiting younger patients who might otherwise need multiple surgeries throughout their lifetime.
• Clinical trials confirm ataciguat's safety profile with minimal side effects, maintaining bone health while effectively slowing valve calcification, paving the way for upcoming Phase 3 trials.