Indocyanine green acid form

Generic Name
Indocyanine green acid form
Brand Names
Ic-green
Drug Type
Small Molecule
Chemical Formula
C43H48N2O6S2
CAS Number
28782-33-4
Unique Ingredient Identifier
C4V974V932
Background

Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.

Indication

For Determining Cardiac Output, Hepatic Function and Liver Blood Flow

For ophthalmic angiography

Associated Conditions
-
Associated Therapies
-

Near Infrared Fluorescence Imaging With Indocyanine Green

First Posted Date
2016-08-01
Last Posted Date
2017-11-21
Lead Sponsor
University of Pittsburgh
Target Recruit Count
25
Registration Number
NCT02851368
Locations
🇺🇸

Department of Cardiothoracic Surgery, Pittsburgh, Pennsylvania, United States

A Prospective Clinical Study for Evaluation of Safe Resection Margin in Breast Conserving Surgery in Breast Cancer

Phase 2
Conditions
Interventions
First Posted Date
2016-06-29
Last Posted Date
2016-06-29
Lead Sponsor
National Cancer Center, Korea
Target Recruit Count
149
Registration Number
NCT02817334
Locations
🇰🇷

National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of

Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer

First Posted Date
2016-05-24
Last Posted Date
2016-09-20
Lead Sponsor
Samsung Medical Center
Target Recruit Count
150
Registration Number
NCT02781259
Locations
🇰🇷

Samsung medical center, Seoul, Korea, Republic of

Measurements of Kidney Perfusion After Transplantation by Intraoperative Fluorescence Angiography

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-05-18
Last Posted Date
2020-05-08
Lead Sponsor
University Hospital Erlangen
Target Recruit Count
128
Registration Number
NCT02775838
Locations
🇩🇪

University of Erlangen, Vascular Surgery, Erlangen, Germany

🇩🇪

University of Mannheim, General Surgery, Mannheim, Germany

NIR Fluorescence Imaging of Lymphatic Transport Using ICG

First Posted Date
2016-02-11
Last Posted Date
2022-10-18
Lead Sponsor
University of Rochester
Target Recruit Count
23
Registration Number
NCT02680067
Locations
🇺🇸

University of Rochester, Rochester, New York, United States

The Impact of Indocyanine Green-enhanced Fluorescence Imaging on Bowel Transection in Left-sided Colorectal Resection

First Posted Date
2016-02-01
Last Posted Date
2016-02-01
Lead Sponsor
The University of Hong Kong
Target Recruit Count
30
Registration Number
NCT02669485
Locations
🇭🇰

Queen Mary Hospital, Hong Kong, Hong Kong

Minimally Invasive Imagery With Indocyanine Green

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-12-03
Last Posted Date
2018-03-20
Lead Sponsor
University of Pennsylvania
Target Recruit Count
48
Registration Number
NCT02621268
Locations
🇺🇸

Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

NIR Fluorescence Imaging Technique in Thoracic Surgery With ICG

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-11-20
Last Posted Date
2018-06-08
Lead Sponsor
Chinese Academy of Sciences
Target Recruit Count
36
Registration Number
NCT02611245
Locations
🇨🇳

Key Laboratory of Molecular Imaging, Chinese Academy of Sciences, Beijing, Beijing, China

Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2015-10-07
Last Posted Date
2024-12-06
Lead Sponsor
St. Joseph's Healthcare Hamilton
Target Recruit Count
250
Registration Number
NCT02570815
Locations
🇨🇦

St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada

ENB Robotic ICG Guided Surgery: A Novel Technique for Targeting Small Lung Tumors

First Posted Date
2015-10-07
Last Posted Date
2017-06-05
Lead Sponsor
St. Joseph's Healthcare Hamilton
Registration Number
NCT02570958
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