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Revdofilimab

Generic Name
Revdofilimab

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Phase 1
Completed
Conditions
Advanced Solid Tumors Cancer
Interventions
First Posted Date
2019-12-12
Last Posted Date
2023-02-27
Lead Sponsor
AbbVie
Target Recruit Count
30
Registration Number
NCT04196283
Locations
πŸ‡ΊπŸ‡Έ

The University of Chicago Medical Center /ID# 217196, Chicago, Illinois, United States

πŸ‡ΊπŸ‡Έ

MD Anderson Cancer Center /ID# 214041, Houston, Texas, United States

πŸ‡ΊπŸ‡Έ

Norton Cancer Institute /ID# 216179, Louisville, Kentucky, United States

and more 23 locations

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1
Active, not recruiting
Conditions
Advanced Solid Tumors
Cancer
Triple-Negative Breast Cancer (TNBC)
Non-small-cell-lung-cancer (NSCLC)
Metastatic Solid Tumors
Interventions
First Posted Date
2019-03-28
Last Posted Date
2024-08-14
Lead Sponsor
AbbVie
Target Recruit Count
150
Registration Number
NCT03893955
Locations
πŸ‡ͺπŸ‡Έ

Hospital Universitario Fundacion Jimenez Diaz /ID# 212806, Madrid, Spain

πŸ‡¦πŸ‡Ί

Icon Cancer Centre /ID# 224084, South Brisbane, Queensland, Australia

πŸ‡ΊπŸ‡Έ

Fort Wayne Medical Oncology and Hematology, Inc /ID# 226072, Fort Wayne, Indiana, United States

and more 23 locations

A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 1
Terminated
Conditions
Head and Neck Cancer
Interventions
First Posted Date
2019-01-28
Last Posted Date
2020-12-31
Lead Sponsor
AbbVie
Target Recruit Count
3
Registration Number
NCT03818542
Locations
πŸ‡ΊπŸ‡Έ

Massachusetts General Hospital /ID# 207392, Boston, Massachusetts, United States

πŸ‡ΊπŸ‡Έ

University of Michigan /ID# 210181, Ann Arbor, Michigan, United States

πŸ‡ΊπŸ‡Έ

MD Anderson Cancer Center /ID# 208749, Houston, Texas, United States

A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumors Cancer
Interventions
First Posted Date
2017-03-07
Last Posted Date
2022-04-28
Lead Sponsor
AbbVie
Target Recruit Count
139
Registration Number
NCT03071757
Locations
πŸ‡«πŸ‡·

Institut Gustave Roussy /ID# 165035, Villejuif Cedex, Val-de-Marne, France

πŸ‡«πŸ‡·

AP-HM - Hopital de la Timone /ID# 165036, Marseille CEDEX 05, Bouches-du-Rhone, France

πŸ‡ΊπŸ‡Έ

Carolina BioOncology Institute /ID# 160786, Huntersville, North Carolina, United States

and more 24 locations
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