Trazodone
- Generic Name
- Trazodone
- Brand Names
- Desyrel, Oleptro
- Drug Type
- Small Molecule
- Chemical Formula
- C19H22ClN5O
- CAS Number
- 19794-93-5
- Unique Ingredient Identifier
- YBK48BXK30
- Background
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibito...
- Indication
Trazodone is indicated for the treatment of major depressive disorder (MDD). It has been used off-label for adjunct therapy in alcohol dependence, and off-label to treat anxiety and insomnia. It may also be used off-label to treat symptoms of dementia, Alzheimer’s disease, schizophrenia, eating disorders, and fibromyalgia due to its effects on various neurot...
- Associated Conditions
- Alcohol Dependency, Alzheimer's Disease (AD), Anxiety, Dementia, Eating Disorders Symptoms, Fibromyalgia, Insomnia, Major Depressive Disorder (MDD), Pain, Inflammatory, Schizophrenia, Moderate to severe pain
- Associated Therapies
- -
Insomnia and Drug Relapse Risk
- Conditions
- Interventions
- First Posted Date
- 2005-11-15
- Last Posted Date
- 2013-12-11
- Lead Sponsor
- Butler Hospital
- Target Recruit Count
- 137
- Registration Number
- NCT00253890
- Locations
- 🇺🇸
Butler Hospital, Providence, Rhode Island, United States
Trazodone for Sleep Disturbance in Early Alcohol Recovery
- First Posted Date
- 2001-11-20
- Last Posted Date
- 2010-05-13
- Lead Sponsor
- Rhode Island Hospital
- Target Recruit Count
- 173
- Registration Number
- NCT00027053
- Locations
- 🇺🇸
Rhode Island Hospital, Providence, Rhode Island, United States
Agitation in Alzheimer's Disease
- Conditions
- First Posted Date
- 1999-11-01
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Institute on Aging (NIA)
- Registration Number
- NCT00000179
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
🇺🇸University Hospitals of Cleveland, Cleveland, Ohio, United States
🇺🇸Mount Sinai Medical Center, New York, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.