Terbutaline

Generic Name
Terbutaline
Brand Names
Bricanyl
Drug Type
Small Molecule
Chemical Formula
C12H19NO3
CAS Number
23031-25-6
Unique Ingredient Identifier
N8ONU3L3PG
Background

Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.

Terbutaline was granted FDA approval on 25 March 1974.

Indication

Terbutaline is indicated for prevention and reversal of bronchospasm in patients at least 12 years old, with asthma and reversible bronchospasm associated with bronchitis and emphysema.

Associated Conditions
Asthma, Bronchospasm, Chronic Cough (CC), Chronic Obstructive Pulmonary Disease (COPD), Cough, Premature Labour, Productive cough
Associated Therapies
Airway secretion clearance therapy

The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia

First Posted Date
2022-08-09
Last Posted Date
2022-08-09
Lead Sponsor
Peking University People's Hospital
Target Recruit Count
228
Registration Number
NCT05494307

Acute Tocolysis With Terbutaline for Suspected Fetal Distress

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2022-04-13
Last Posted Date
2022-04-13
Lead Sponsor
Hospital Kemaman
Target Recruit Count
100
Registration Number
NCT05326269
Locations
🇲🇾

Hospital Kemaman, Kuala Terengganu, Terengganu, Malaysia

Hot Flashes and Neurovascular Function in Women

First Posted Date
2022-01-18
Last Posted Date
2024-05-24
Lead Sponsor
Mayo Clinic
Target Recruit Count
120
Registration Number
NCT05193968
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Terbutaline Sulfate in Adults With Asthma

Phase 2
Suspended
Conditions
Interventions
First Posted Date
2021-07-22
Last Posted Date
2024-07-24
Lead Sponsor
Kanecia Obie Zimmerman
Target Recruit Count
30
Registration Number
NCT04973345
Locations
🇺🇸

Duke Early Phase Research Unit (DEPRU), Durham, North Carolina, United States

The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

First Posted Date
2020-07-22
Last Posted Date
2020-07-22
Lead Sponsor
Peking University People's Hospital
Target Recruit Count
40
Registration Number
NCT04481282
Locations
🇨🇳

Peking University Insititute of Hematology, Peking University People's Hospital, Beijing, Beijing, China

In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline

First Posted Date
2020-07-13
Last Posted Date
2022-06-06
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
25
Registration Number
NCT04468568
Locations
🇧🇷

Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

Beta2-adrenergic Agonism and Muscle Remodelling

First Posted Date
2018-06-21
Last Posted Date
2020-03-25
Lead Sponsor
Morten Hostrup, PhD
Target Recruit Count
72
Registration Number
NCT03565302
Locations
🇩🇰

August Krogh Building, Copenhagen, Denmark

Success of External Cephalic Version Study

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2017-04-10
Last Posted Date
2020-10-09
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
34
Registration Number
NCT03106753
Locations
🇺🇸

Mount Sinai West, New York, New York, United States

Role of K+ and Ca2+ in Development of Muscle Fatigue

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2016-03-18
Last Posted Date
2017-01-31
Lead Sponsor
University of Copenhagen
Target Recruit Count
10
Registration Number
NCT02712658
Locations
🇩🇰

Department of Nutrition, Exercise and Sports, Copenhagen, Denmark

cAMP Signaling and Muscle Adaptations

First Posted Date
2015-09-23
Last Posted Date
2017-10-26
Lead Sponsor
University of Copenhagen
Target Recruit Count
72
Registration Number
NCT02557581
Locations
🇩🇰

Bispebjerg University Hospital, Copenhagen, Denmark

🇩🇰

Department of Nutrition, Exercise and Sports, Copenhagen, Denmark

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