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Implitapide is a microsomal triglyceride transfer protein (MTP)-inhibitor.
Implitapide is a microsomal triglyceride transfer protein (MTP)-inhibitor.
MTP mediates triglyceride absorption and chylomicron secretion from the intestine and very-low-density lipoprotein (VLDL) secretion from the liver by linking lipid molecules with apolipoprotein B (apoB). Inhibition of MTP reduces the level of all apoB-containing lipoproteins, including LDL.
For the treatment of atherosclerosis.
One entry per invention. Patent families filed in the US, EP, WO and CN offices.
