Triptorelin

Generic Name: Triptorelin

Brand Names: Decapeptyl, Trelstar, Triptodur

Drug Type: Small Molecule

Chemical Formula: C_₆₄H_₈₂N_₁₈O_₁₃

CAS Number: 57773-63-4

Unique Ingredient Identifier: 9081Y98W2V

Background: Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. S...

Indication: Triptorelin is indicated for the palliative treatment of advanced prostate cancer.

Associated Conditions: Advanced Prostate Cancer

Associated Therapies: Controlled ovarian hyperstimulation therapy

Clinical Trials

Gonadotropin-releasing Hormone (GnRH) Downregulation Versus Oral Anticonception Prior to ART in Postoperative Endometriosis Patients

Not Applicable

Completed

Conditions: Endometriosis
Infertility

Interventions: Drug: ethinylestradiol + dienogest
Drug: triptorelin

First Posted Date: 2015-03-27

Last Posted Date: 2024-07-10

Lead Sponsor: Universitaire Ziekenhuizen KU Leuven

Target Recruit Count: 166

Registration Number: NCT02400801

Locations: 🇧🇪
UZ Leuven, Leuven, Belgium

Micro RNAs to Predict Response to Androgen Deprivation Therapy

Completed

Conditions: Prostate Cancer

Interventions: Drug: Bicalutamide
Drug: Leuprolide
Drug: Goserelin
Drug: Triptorelin
Drug: Docetaxel
Drug: Abiraterone
Drug: Apalutamide
Drug: Enzalutamide

First Posted Date: 2015-02-19

Last Posted Date: 2024-11-25

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 42

Registration Number: NCT02366494

Locations: 🇺🇸
Froedtert Hospital, Milwaukee, Wisconsin, United States

Comparative Study Between Minidose Long Protocol and Microdose Flare Protocol in Controlled Ovarian Hyperstimulation

Phase 3

Completed

Conditions: Infertility

Interventions: Drug: Decapeptyl

First Posted Date: 2015-01-19

Last Posted Date: 2015-01-28

Lead Sponsor: Kasr El Aini Hospital

Target Recruit Count: 60

Registration Number: NCT02342197

GnRHa for Luteal Phase Support in GnRH Antagonist Protocol Cycles

Phase 4

Recruiting

Conditions: Infertility

Interventions: Drug: Triptorelin

First Posted Date: 2014-12-09

Last Posted Date: 2023-10-30

Lead Sponsor: Mansoura University

Target Recruit Count: 200

Registration Number: NCT02312089

Locations: 🇪🇬
Fertility Care Unit (FCU) in Mansoura University Hospital, Mansourah, Dakahlia, Egypt
🇪🇬
Private fertility care centers, Mansourah, Dakahlia, Egypt

GnRHa for Luteal Phase Support in Long GnRHa Protocol Cycles

Phase 4

Recruiting

Conditions: Infertility

Interventions: Drug: Triptorelin

First Posted Date: 2014-12-09

Last Posted Date: 2023-10-30

Lead Sponsor: Mansoura University

Target Recruit Count: 200

Registration Number: NCT02312076

Locations: 🇪🇬
Fertility Care Unit (FCU) in Mansoura University Hospital, Mansourah, Dakahlia, Egypt
🇪🇬
Private fertility care centers, Mansourah, Dakahlia, Egypt

Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer

Phase 2

Active, not recruiting

Conditions: Stage III Prostate Cancer
Recurrent Prostate Cancer
Adenocarcinoma of the Prostate
Stage IV Prostate Cancer

Interventions: Drug: leuprolide acetate
Drug: Enzalutamide
Drug: goserelin acetate
Drug: histrelin acetate
Drug: triptorelin
Drug: degarelix

First Posted Date: 2014-10-29

Last Posted Date: 2024-05-06

Lead Sponsor: University of Colorado, Denver

Target Recruit Count: 19

Registration Number: NCT02278185

Locations: 🇺🇸
University of Colorado Health - Poudre Valley Hospital, Fort Collins, Colorado, United States
🇺🇸
University of Colorado Cancer Center - Anschutz Cancer Pavilion, Aurora, Colorado, United States

Study To Assess Renewal Of Treatment In Patients Recently Diagnosed With Prostate Cancer

Completed

Conditions: Prostate Cancer

Interventions: Drug: triptorelin

First Posted Date: 2014-09-12

Last Posted Date: 2019-07-25

Lead Sponsor: Ipsen

Target Recruit Count: 368

Registration Number: NCT02238366

GnRHa Trigger in Asian Oocyte Donors- a Dose Finding Study

Not Applicable

Completed

Conditions: Normal Oocyte Donors

Interventions: Drug: Triptorelin

First Posted Date: 2014-08-05

Last Posted Date: 2017-02-06

Lead Sponsor: Vietnam National University

Target Recruit Count: 165

Registration Number: NCT02208986

Locations: 🇻🇳
My Duc Hospital, IVFMD, Ho Chi Minh City, Ho Chi Minh, Vietnam

GnRH Agonist Triggering Supplemented With Hcg in Women With Poor Ovarian Response

Not Applicable

Conditions: Women With Poor Ovarian Response

Interventions: Drug: Ovitrel
Drug: Decapeptyl

First Posted Date: 2014-05-22

Last Posted Date: 2014-05-22

Lead Sponsor: Sheba Medical Center

Target Recruit Count: 60

Registration Number: NCT02144818

Locations: 🇮🇱
Sheba medical center, Ramat Gan, Israel

Anti-Mullerian Hormone (AMH) as Marker of Ovarian Reserve

Phase 2

Terminated

Conditions: Breast Cancer

Interventions: Drug: Triptorelin

First Posted Date: 2014-04-14

Last Posted Date: 2022-09-10

Lead Sponsor: Armando Santoro, MD

Target Recruit Count: 45

Registration Number: NCT02113553

Locations: 🇮🇹
Istituto Clinico Humanitas, Rozzano, Milan, Italy

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