Triptorelin
- Generic Name
- Triptorelin
- Brand Names
- Decapeptyl, Trelstar, Triptodur
- Drug Type
- Small Molecule
- Chemical Formula
- C64H82N18O13
- CAS Number
- 57773-63-4
- Unique Ingredient Identifier
- 9081Y98W2V
- Background
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. S...
- Indication
Triptorelin is indicated for the palliative treatment of advanced prostate cancer.
- Associated Conditions
- Advanced Prostate Cancer
- Associated Therapies
- Controlled ovarian hyperstimulation therapy
MRI Substudy; Metabolic Changes Due to Iatrogenic Hypogonadism
- Conditions
- Interventions
- First Posted Date
- 2014-04-03
- Last Posted Date
- 2015-10-28
- Lead Sponsor
- Herlev Hospital
- Target Recruit Count
- 31
- Registration Number
- NCT02102646
- Locations
- 🇩🇰
Herlev Hospital, Herlev, Denmark
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
- First Posted Date
- 2013-12-27
- Last Posted Date
- 2013-12-27
- Lead Sponsor
- Chenshiling
- Target Recruit Count
- 80
- Registration Number
- NCT02022241
- Locations
- 🇨🇳
Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
Dual Trigger to Reduce Ovarian Hyperstimulation Syndrome
- First Posted Date
- 2013-12-27
- Last Posted Date
- 2013-12-27
- Lead Sponsor
- Chenshiling
- Target Recruit Count
- 200
- Registration Number
- NCT02022228
- Locations
- 🇨🇳
Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
TRial on the Endocrine Activity of Neoadjuvant Degarelix
- Conditions
- Interventions
- First Posted Date
- 2013-12-09
- Last Posted Date
- 2019-05-29
- Lead Sponsor
- ETOP IBCSG Partners Foundation
- Target Recruit Count
- 51
- Registration Number
- NCT02005887
- Locations
- 🇮🇹
Azienda Ospedaliero-Universitaria Policlinico S. Orsola-Malpighi di Bologna, Bologna, Italy
🇮🇹Istituto Toscana Tumori, Prato, Italy
🇮🇹Ospedale degli Infermi, Rimini, Italy
Prevention of Ovarian Function Damage by a GnRH Analogue During Chemotherapy in Hodgkin Lymphoma Patients
- First Posted Date
- 2013-01-09
- Last Posted Date
- 2013-01-09
- Lead Sponsor
- Masaryk University
- Target Recruit Count
- 72
- Registration Number
- NCT01764230
- Locations
- 🇨🇿
Brno University Hospital and Masaryk University School of Medicine, Brno, Czech Republic
Corifollitropin Alfa Followed by hpHMG in a Long GnRH Agonist Protocol for the Treatment of Poor Ovarian Responders
- Conditions
- Interventions
- First Posted Date
- 2012-11-22
- Last Posted Date
- 2013-05-09
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 57
- Registration Number
- NCT01732094
- Locations
- 🇧🇪
Centre for Reproductive Medicine UZ Brussel, Brussels, Belgium
Treatment of Poor Ovarian Responders With Corifollitropin Alfa Followed by hpHMG in a Short GnRH Agonist Protocol
- Conditions
- Interventions
- First Posted Date
- 2012-11-22
- Last Posted Date
- 2013-05-09
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 51
- Registration Number
- NCT01732068
- Locations
- 🇧🇪
Centre for Reproductive Medicine UZ Brussel, Brussels, Belgium
The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis
- First Posted Date
- 2012-04-20
- Last Posted Date
- 2015-10-22
- Lead Sponsor
- Instituto de Investigacion Sanitaria La Fe
- Target Recruit Count
- 200
- Registration Number
- NCT01581359
- Locations
- 🇪🇸
Human Reproduction Unit of the La Fe University and Politechnic Hospital, Valencia, Spain
Endometrial Receptivity After GnRH Agonist Triggering
- First Posted Date
- 2011-12-29
- Last Posted Date
- 2016-10-26
- Lead Sponsor
- IVI Madrid
- Target Recruit Count
- 35
- Registration Number
- NCT01500863
- Locations
- 🇪🇸
Instituto Valenciano de Infertilidad, Madrid, Spain
Ovarian Stimulation Using Recombinant Follicle-stimulating Hormone (FSH) and Gonadotrophin Releasing Hormone (GnRH) Agonist in Alternate Days
- First Posted Date
- 2011-11-09
- Last Posted Date
- 2012-07-13
- Lead Sponsor
- Fertility - Assisted Fertilization Center
- Target Recruit Count
- 96
- Registration Number
- NCT01468441
- Locations
- 🇧🇷
Fertility - Assisted Fertilization Center, Sao Paulo, Brazil
Drug Development Updates
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