利美索龙

概览

Rimexolone is a glucocorticoid used to treat inflammation of the eye.

作用机制

Rimexolone is a glucocorticoid receptor agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. By binding to the glucocorticoid receptor, this drug ultimately leads to changes in genetic transcription involving the lipocortins and prostaglandins.

适应症

For the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis.

• Anterior Uveitis (AU)
• Ocular Inflammation