Liothyronine
- Generic Name
- Liothyronine
- Brand Names
- Cytomel, Np Thyroid
- Drug Type
- Small Molecule
- Chemical Formula
- C15H12I3NO4
- CAS Number
- 6893-02-3
- Unique Ingredient Identifier
- 06LU7C9H1V
- Background
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956.
- Indication
Liothyronine is officially approved for the following indications:
In general terms, exogenous liothyronine is used to replace insufficient hormonal production and restore T3 plasma levels.
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- Associated Conditions
- Autonomy of thyroid gland, Hyperthyroidism, Hypothyroidism, Myxedema coma, Thyroid Cancer, Euthyroid Goitre, Myxedema pre-coma
- Associated Therapies
- Supplemental or replacement therapy
Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression.
- Conditions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2007-01-04
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 220
- Registration Number
- NCT00158990
- Locations
- 🇺🇸
Global Medical Institutes, Princeton, New Jersey, United States
🇮🇱Hadassah Medical Organisation, Jerusalem, Israel
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