Bile acid sequestrants like colestipol have been in use since the 1970s. And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as an adjunct therapy and the relatively physical nature of...
1.Ⅱa型高脂蛋白血症、冠心病危险性大而控制饮食治疗无效者。本品降低血浆总胆固醇和低密度脂蛋白胆固醇浓度,对血清甘油三酯浓度无影响或使之轻度升高,因此,对单纯甘油三酯升高者无效;2.胆管不完全阻塞所致的瘙痒。
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